Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | GSR | P00390 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8918321 | 0.83 | KMT2A (0.37) | TDP1KMT2AMAPTKDM4ENPSR1 | |
| SCHEMBL8627417 | 0.83 | MAPK1 (0.49) | KMT2AMEN1MAPK1SMN1; SMN2 | |
| SCHEMBL8623864 | 0.82 | CASR (0.39) | TDP1KMT2AMAPTMEN1ALDH1A1 | |
| SCHEMBL24612781 | 0.80 | ALDH1A1 (0.43) | KMT2AMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL25890712 | 0.80 | ALDH1A1 (0.43) | KMT2AMAPTMEN1ALDH1A1HPGD | |
| SCHEMBL8625688 | 0.79 | FBP1 (0.38) | MAPK1 | |
| SCHEMBL2007842 | 0.73 | KDM4E (0.43) | TDP1KMT2AMAPTKDM4ENPSR1 | |
| SCHEMBL8625790 | 0.73 | PRMT1 (0.43) | TDP1KMT2AMAPTKDM4EMEN1 | |
| SCHEMBL11743677 | 0.72 | KMT2A (0.50) | TDP1KMT2AMAPTKDM4ENPSR1 | |
| Potassium Ion SCHEMBL11297820 | 0.72 | KDM4E (0.42) | TDP1KMT2AMAPTKDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672646-B1 | Process for producing beta-nitro-enamines and intermediates thereof | SUMITOMO CHEMICAL CO (JP) | 1998-06-10 | — | — | EP | disclosed |
| US-5639895-A | Process for producing β-nitroenamine | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-06-17 | — | — | US | disclosed |
| US-5597940-A | REACTING NITROOLEFIN WITH HYDROXYLAMINE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0672646-A1 | Process for producing beta-nitro-enamines and intermediates thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-09-20 | — | — | EP | disclosed |