⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL78600 | 1.00 | — | — | |
| SCHEMBL4180170 | 1.00 | — | — | |
| Ammonia Solution, Strong SCHEMBL10573407 | 0.96 | — | — | |
| Trimethylammonium SCHEMBL456269 | 0.87 | — | — | |
| Dimethylamine SCHEMBL21632308 | 0.87 | — | — | |
| Bicarbonate SCHEMBL10628071 | 0.85 | — | — | |
| SCHEMBL9584467 | 0.85 | ALDH1A1 (0.72) | — | |
| SCHEMBL455128 | 0.83 | ALDH1A1 (0.36) | — | |
| Diethylamine SCHEMBL21632306 | 0.81 | TP53 (0.40) | — | |
| Ether SCHEMBL5400744 | 0.81 | SMN1; SMN2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111056942-B | Preparation method of 3-hydroxy-6-oxohexanoate | 新发药业有限公司 | 2021-08-17 | — | — | CN | claimed |
| CN-111056942-A | Preparation method of 3-hydroxy-6-oxohexanoate | 新发药业有限公司 | 2020-04-24 | — | — | CN | claimed |
| US-12454529-B2 | Piperazine cyclic ureas | Sironax Ltd. (KY) | 2025-10-28 | — | — | US | disclosed |
| CN-115697991-B | Piperazine cyclic ureas | 维泰瑞隆有限公司 | 2024-11-22 | — | — | CN | disclosed |
| US-20230203019-A1 | Piperazine Cyclic Ureas | SIRONAX (BEIJING) CO., LTD. (CN) | 2023-06-29 | — | — | US | disclosed |
| US-20230203019-A1 | Piperazine Cyclic Ureas | SIRONAX (BEIJING) CO., LTD. (CN) | 2023-06-29 | — | — | US | disclosed |
| CN-115697991-A | Piperazine cyclic ureas | 维泰瑞隆有限公司 | 2023-02-03 | — | — | CN | disclosed |
| CN-111056942-B | Preparation method of 3-hydroxy-6-oxohexanoate | 新发药业有限公司 | 2021-08-17 | — | — | CN | disclosed |
| CN-111056942-A | Preparation method of 3-hydroxy-6-oxohexanoate | 新发药业有限公司 | 2020-04-24 | — | — | CN | disclosed |
| EP-2890672-B1 | PROCESSES FOR PREPARING INTERMEDIATES FOR THE MANUFACTURE OF NEP INHIBITORS | NOVARTIS AG (CH) | 2018-05-30 | — | — | EP | disclosed |
| US-9624163-B2 | Process for preparing intermediates useful in the manufacture of NEP inhibitors | NOVARTIS AG (CH) | 2017-04-18 | — | — | US | disclosed |
| EP-1292602-A1 | NEW CHIRAL SALEN CATALYST AND METHODS FOR THE PREPARATION OF CHIRAL COMPOUNDS FROM RACEMIC EPOXIDES BY USING NEW CATALYST | RS Tech Corp. (KR) | 2003-03-19 | — | — | EP | disclosed |
| US-20030032821-A1 | Novel chiral salen catalysts, and a process for preparing chiral compounds from racemic epoxides for using them | RSTECH CO., LTD. (KR) | 2003-02-13 | — | — | US | disclosed |
| WO-2003002582-A1 | NEW CHIRAL SALEN CATALYST AND METHODS FOR THE PREPARATION OF CHIRAL COMPOUNDS FROM RACEMIC EPOXIDES BY USING NEW CATALYST | RS TECH CORP. (KR) | 2003-01-09 | — | — | WO | disclosed |
| US-5602108-A | Semisynthetic diastereomerically pure N-glycidylanthracyclines, a process for the stereoselective preparation thereof as the use thereof as cytostatics | BEHRINGWERKE AKTIENGESELLSCHAFT (DE) | 1997-02-11 | — | — | US | disclosed |
| US-5250715-A | Optically active 2-methylenepentane derivative and process for preparing same | DAISO CO., LTD. (JP) | 1993-10-05 | — | — | US | disclosed |
| US-5216187-A | Optically active 2-methylenepentane derivative and process for preparing same | DAISO CO., LTD. (JP) | 1993-06-01 | — | — | US | disclosed |
| US-5200538-A | Optically active 2-methylenecyclopentanone derivative and process for preparing same | DAISO CO., LTD. (JP) | 1993-04-06 | — | — | US | disclosed |
| US-5180844-A | Optically active 2-methylenecyclopentanone derivative and process for preparing same | DAISO CO., LTD. (JP) | 1993-01-19 | — | — | US | disclosed |
| US-5136066-A | Process for preparing optically active cyclopentenone derivative | DAISO CO., LTD. (JP) | 1992-08-04 | — | — | US | disclosed |