SCHEMBL4180170

SCHEMBL4180170

BrC[C@H]1CO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL78600 1.00
SCHEMBL2461280 1.00
Ammonia Solution, Strong SCHEMBL10573407 0.96
Trimethylammonium SCHEMBL456269 0.87
Dimethylamine SCHEMBL21632308 0.87
Bicarbonate SCHEMBL10628071 0.85
SCHEMBL9584467 0.85 ALDH1A1 (0.72)
SCHEMBL455128 0.83 ALDH1A1 (0.36)
Diethylamine SCHEMBL21632306 0.81 TP53 (0.40)
Ether SCHEMBL5400744 0.81 SMN1; SMN2 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673377-B1 PROCESS FOR THE PREPARATION OF 3-AMINO-2-HYDROXYPROPYLPHOSPHINIC ACID DERIVATIVES AVENTIS PHARMA INC (US) 2013-12-25 EP claimed
US-7186705-B2 Process for the preparation of 3-amino-2-hydroxypropylphosphinic acid derivatives AVENTIS PHARMACEUTICALS INC. (US) 2007-03-06 US claimed
US-20050070507-A1 Process for the preparation of 3-amino-2-hydroxypropylphosphinic acid derivatives AVENTIS PHARMACEUTICALS INC. (US) 2005-03-31 US claimed
WO-2025184391-A9 COVALENT INHIBITORS AND USES THEREOF ARRAKIS THERAPEUTICS, INC. (US) 2025-10-30 WO disclosed
US-12454529-B2 Piperazine cyclic ureas Sironax Ltd. (KY) 2025-10-28 US disclosed
CN-115697991-B Piperazine cyclic ureas 维泰瑞隆有限公司 2024-11-22 CN disclosed
US-20230203019-A1 Piperazine Cyclic Ureas SIRONAX (BEIJING) CO., LTD. (CN) 2023-06-29 US disclosed
US-20230203019-A1 Piperazine Cyclic Ureas SIRONAX (BEIJING) CO., LTD. (CN) 2023-06-29 US disclosed
CN-115697991-A Piperazine cyclic ureas 维泰瑞隆有限公司 2023-02-03 CN disclosed
CN-111333566-A Preparation method of key intermediate of levomilnacipran 北京万全德众医药生物技术有限公司 2020-06-26 CN disclosed
EP-1673377-B1 PROCESS FOR THE PREPARATION OF 3-AMINO-2-HYDROXYPROPYLPHOSPHINIC ACID DERIVATIVES AVENTIS PHARMA INC (US) 2013-12-25 EP disclosed
US-20040054201-A1 Chiral polymeric salen catalyst, and a process for preparing chiral compounds from racemic epoxides by using them RSTECH CO., LTD. (KR) 2004-03-18 US disclosed
US-20030216250-A1 Chiral salen catalyst and methods for the preparation of chiral compounds from racemic epoxides by using new catalyst RS TECH CORP. (KR) 2003-11-20 US disclosed
EP-1292602-A4 NEW CHIRAL SALEN CATALYST AND METHODS FOR THE PREPARATION OF CHIRAL COMPOUNDS FROM RACEMIC EPOXIDES BY USING NEW CATALYST RS TECH CORP (KR) 2003-07-09 EP disclosed
EP-1292602-A1 NEW CHIRAL SALEN CATALYST AND METHODS FOR THE PREPARATION OF CHIRAL COMPOUNDS FROM RACEMIC EPOXIDES BY USING NEW CATALYST RS Tech Corp. (KR) 2003-03-19 EP disclosed
EP-1289655-A1 NOVEL CHIRAL SALEN CATALYSTS, AND A PROCESS FOR PREPARING CHIRAL COMPOUNDS FROM RACEMIC EPOXIDES FOR USING THEM Rstech Co., Ltd. (KR) 2003-03-12 EP disclosed
US-20030032821-A1 Novel chiral salen catalysts, and a process for preparing chiral compounds from racemic epoxides for using them RSTECH CO., LTD. (KR) 2003-02-13 US disclosed
WO-2003002582-A1 NEW CHIRAL SALEN CATALYST AND METHODS FOR THE PREPARATION OF CHIRAL COMPOUNDS FROM RACEMIC EPOXIDES BY USING NEW CATALYST RS TECH CORP. (KR) 2003-01-09 WO disclosed
WO-2002048162-A1 CHIRAL POLYMERIC SALEN CATALYST, AND A PROCESS FOR PREPARING CHIRAL COMPOUNDS FROM RACEMIC EPOXIDES BY USING THEM RSTECH CO., LTD (KR) 2002-06-20 WO disclosed
WO-2001089690-A1 NOVEL CHIRAL SALEN CATALYSTS, AND A PROCESS FOR PREPARING CHIRAL COMPOUNDS FROM RACEMIC EPOXIDES FOR USING THEM RSTECH CO., LTD. (KR) 2001-11-29 WO disclosed