SCHEMBL24614739

SCHEMBL24614739

CC1(C)c2ccc(-c3c4ccccc4c(-c4cc5cc(-c6c7ccccc7c(-c7ccccc7)c7ccccc67)c6oc7ccccc7c6c5c5c4oc4ccccc45)c4ccccc34)cc2C(C)(C)C1(C)C

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
ADORA2A P29274 1/20 0.31
CDC14B O60729 1/20 0.31
CDC14A Q9UNH5 1/20 0.31
CYP1A1 P04798 1/20 0.30
CYP1A2 P05177 1/20 0.30
CYP1B1 Q16678 1/20 0.30
KDM4E B2RXH2 1/20 0.30
MEN1 O00255 1/20 0.30
CYP3A4 P08684 1/20 0.30
ALPI P09923 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
PKM P14618 1/20 0.30
HPGD P15428 1/20 0.30
CASP3 P42574 1/20 0.30
RECQL P46063 1/20 0.30
BLM P54132 1/20 0.30
CASP7 P55210 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24614917 0.98 KDM4E (0.31) CA1CA2CDC14BCDC14AKDM4E
SCHEMBL24614636 0.92 CA1 (0.30) CA1CA2
SCHEMBL24614797 0.83 CA1 (0.41) CA1CA2ADORA2ACDC14BCDC14A
SCHEMBL24614668 0.83 CA1 (0.43) CA1CA2ADORA2ACDC14BCDC14A
SCHEMBL24614688 0.82 CA1 (0.38) CA1CA2ADORA2ACDC14BCDC14A
SCHEMBL24614815 0.82 CA1 (0.38) CA1CA2ADORA2ACDC14BCDC14A
SCHEMBL24614915 0.82 CDC14B (0.40) CA1CA2ADORA2ACDC14BCDC14A
SCHEMBL24614905 0.81 MAOB (0.42) CA1CA2ADORA2ACDC14BCDC14A
SCHEMBL24614738 0.81 CDC14B (0.41) CA1CA2ADORA2ACDC14BCDC14A
SCHEMBL24614676 0.80 CDC14B (0.40) CA1CA2ADORA2ACDC14BCDC14A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220223801-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220223801-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES TMEM109, PIEZO1, L1CAM CA1 1283/4885CA2 3674/4885ADORA2A 4425/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.