Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 8/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | PTPRF | P10586 | 1/20 | 0.36 |
| ▸ | PTPRA | P18433 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.36 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.36 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.36 |
| ▸ | TNKS | O95271 | 2/20 | 0.35 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.31 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.31 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.30 |
| ▸ | CCND1 | P24385 | 1/20 | 0.30 |
| ▸ | MAP3K9 | P80192 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24614768 | 0.99 | PTPN1 (0.40) | PTPN1PTPRCPTPRFPTPRAPTPRB | |
| SCHEMBL24614782 | 0.99 | PTPN1 (0.41) | PTPN1PTPRCPTPRFPTPRAPTPRB | |
| SCHEMBL24614750 | 0.94 | PTPN1 (0.39) | PTPN1PTPRCPTPRFPTPRAPTPRB | |
| SCHEMBL24614685 | 0.94 | PTPN1 (0.41) | PTPN1PTPRCPTPRFPTPRAPTPRB | |
| SCHEMBL24614753 | 0.93 | PTPN1 (0.37) | PTPN1PTPRCPTPRFPTPRAPTPRB | |
| SCHEMBL24614710 | 0.90 | PTPN1 (0.38) | PTPN1PTPRCPTPRFPTPRAPTPRB | |
| SCHEMBL24614695 | 0.90 | TNKS (0.40) | PTPN1PTPRCPTPRFPTPRAPTPRB | |
| SCHEMBL24614972 | 0.89 | PTPN1 (0.38) | PTPN1PTPRCPTPRFPTPRAPTPRB | |
| SCHEMBL24614824 | 0.89 | PTPN1 (0.38) | PTPN1PTPRCPTPRFPTPRAPTPRB | |
| SCHEMBL24614808 | 0.89 | PTPN1 (0.38) | PTPN1PTPRCPTPRFPTPRAPTPRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220223801-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220223801-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | TMEM109, PIEZO1, L1CAM | PTPN1 4341/4885PTPRC 4627/4885PTPRF 4514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.