SCHEMBL2461492

SCHEMBL2461492

COC(=O)C(Cc1ccccc1)NC(=O)c1ccccc1

nearest known ligand 0.76

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.76
RAB9A P51151 1/20 0.76
ALDH1A1 P00352 4/20 0.75
LMNA P02545 1/20 0.75
GLA P06280 1/20 0.75
CTSL P07711 3/20 0.70
ATM Q13315 2/20 0.65
THRB P10828 1/20 0.63
CYP2C9 P11712 1/20 0.63
CYP2C19 P33261 1/20 0.63
HSD17B10 Q99714 1/20 0.63
CTSS P25774 1/20 0.62
CTSK P43235 1/20 0.62
POLB P06746 1/20 0.62
ACE P12821 2/20 0.61
L3MBTL1 Q9Y468 1/20 0.58
TACR3 P29371 1/20 0.57
KDM4E B2RXH2 1/20 0.57
PKM P14618 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1793176 1.00 GAA (0.76) GAARAB9AALDH1A1LMNAGLA
SCHEMBL31206887 1.00 GAA (0.76) GAARAB9AALDH1A1LMNAGLA
SCHEMBL4369272 0.94 GAA (0.69) GAARAB9AALDH1A1LMNAGLA
SCHEMBL13669573 0.94 GAA (0.69) GAARAB9AALDH1A1LMNAGLA
SCHEMBL14733433 0.93 GAA (0.67) GAARAB9AALDH1A1LMNAGLA
SCHEMBL16515824 0.93 GAA (0.67) GAARAB9AALDH1A1LMNAGLA
SCHEMBL13525006 0.92 GAA (0.70) GAARAB9AALDH1A1LMNAGLA
SCHEMBL4175147 0.91 GAA (0.73) GAARAB9AALDH1A1LMNAGLA
SCHEMBL3928165 0.91 LNPEP (0.67) GAARAB9AALDH1A1LMNAGLA
SCHEMBL3928164 0.91 LNPEP (0.67) GAARAB9AALDH1A1LMNAGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4403042-A2 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME Mars, Incorporated (US) 2024-07-24 EP disclosed
EP-3229612-B1 USE OF FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS INC (US) 2024-06-26 EP disclosed
US-11185100-B2 Methods for modulating taste receptors MARS, INCORPORATED (US) 2021-11-30 US disclosed
EP-3229610-B1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS INC (US) 2021-06-09 EP disclosed
EP-3229610-B1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS INC (US) 2021-06-09 EP disclosed
CN-106008665-B Compound with tumor proliferation inhibition function and preparation method and application thereof 北京大学 2021-03-16 CN disclosed
EP-3712128-A1 PHOTOCHEMICAL INTERMOLECULAR AMINATION METHOD Fundació Institut Català d'Investigació Química (ICIQ) (ES) 2020-09-23 EP disclosed
US-20190021380-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2019-01-24 US disclosed
US-20180168208-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2018-06-21 US disclosed
US-20180168208-A1 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2018-06-21 US disclosed
US-5532395-A HYDROGENATION CATALYSTS ) E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-07-02 US disclosed
US-5386061-A Reacting a bis(primary phosphine in the presence of a strong base with a cyclic sulfate; cyclization E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-01-31 US disclosed
US-5329015-A Catalysts for stereospecific reactions E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-07-12 US disclosed
EP-0592552-A1 CHIRAL PHOSPHOLANES VIA CHIRAL 1,4-DIOL CYCLIC SULFATES. DU PONT (US) 1994-04-20 EP disclosed
WO-1993001199-A1 CHIRAL PHOSPHOLANES VIA CHIRAL 1,4-DIOL CYCLIC SULFATES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-01-21 WO disclosed
US-5171892-A Chiral phospholanes via chiral 1,4-diol cyclic sulfates E. I. DU PONT DE NEMOURS AND COMPANY (US) 1992-12-15 US disclosed
EP-0145265-B1 ALPHA-AMINO ACIDS THROUGH CATALYTIC REACTION OF CO AND A HYDROXYL COMPOUND WITH ENAMIDES THE STANDARD OIL COMPANY (US) 1989-09-20 EP disclosed
US-4749786-A α-amino acids through catalytic reaction of CO and a hydroxyl compound with enamides THE STANDARD OIL COMPANY (US) 1988-06-07 US disclosed
US-4710574-A HYDROCARBOXYLATION OF UNSATURATED AMIDES THE STANDARD OIL COMPANY (US) 1987-12-01 US disclosed
EP-0145265-A2 Alpha-amino acids through catalytic reaction of CO and a hydroxyl compound with enamides THE STANDARD OIL COMPANY (US) 1985-06-19 EP disclosed