Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 14/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29772782 | 0.99 | KIT (0.39) | KITMAP4K4CHRNA7HTR3ACHRNB2 | |
| SCHEMBL24615206 | 0.78 | KIT (0.56) | KIT | |
| Hydrochloric Acid SCHEMBL29772718 | 0.77 | KIT (0.55) | KIT | |
| SCHEMBL20223114 | 0.76 | LMNA (0.46) | KITMAP4K4CHRNA7HTR3A | |
| Hydrochloric Acid SCHEMBL30726663 | 0.75 | CHRNB2 (0.43) | MAP4K4CHRNB2CHRNA4 | |
| SCHEMBL24615485 | 0.74 | KIT (0.46) | KIT | |
| SCHEMBL24615423 | 0.74 | KIT (0.38) | KITMAP4K4 | |
| SCHEMBL24615202 | 0.74 | KIT (0.48) | KIT | |
| Hydrochloric Acid SCHEMBL29772815 | 0.73 | CHRNB2 (0.33) | CHRNB2CHRNA4 | |
| SCHEMBL24615451 | 0.71 | JAK2 (0.42) | KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150446-A1 | TYK2 INHIBITORS | BIOGEN MA INC. (US) | 2022-07-14 | — | — | WO | disclosed |