Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LPL | P06858 | 2/20 | 0.31 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL140519 | 0.79 | LPL (0.32) | CA1CA2CA9LPLLIPG | |
| SCHEMBL30896150 | 0.78 | FFAR1 (0.33) | LPLLIPGP2RX7 | |
| SCHEMBL22861265 | 0.78 | LPL (0.37) | LPLLIPGP2RX7 | |
| SCHEMBL24616853 | 0.78 | LPL (0.31) | LPLLIPGP2RX7 | |
| SCHEMBL20543216 | 0.76 | FFAR1 (0.33) | LPLLIPGP2RX7 | |
| SCHEMBL20516993 | 0.76 | LPL (0.30) | LPLLIPGP2RX7 | |
| SCHEMBL21382126 | 0.75 | LPL (0.34) | LPLLIPG | |
| SCHEMBL14857712 | 0.74 | ESR2 (0.31) | — | |
| SCHEMBL20456084 | 0.74 | LPL (0.31) | LPLLIPG | |
| SCHEMBL1159688 | 0.74 | LIPE (0.32) | LPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150381-A1 | SELECTIVE INHIBITORS OF ROCK1 AND ROCK2 PROTEIN KINASES AND USES THEREOF | Genosco Inc. (US) | 2022-07-14 | — | — | WO | disclosed |