Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | TRPM5 | Q9NZQ8 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | RIPK2 | O43353 | 4/20 | 0.36 |
| ▸ | RIPK3 | Q9Y572 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23510778 | 1.00 | OGA (0.43) | OGAALDH1A1HSD17B10FFAR1TRPM5 | |
| SCHEMBL24347730 | 0.86 | NPC1 (0.45) | OGAALDH1A1HSD17B10FFAR1SMN1; SMN2 | |
| SCHEMBL12026663 | 0.85 | ALDH1A1 (0.45) | OGAALDH1A1HSD17B10FFAR1TRPM5 | |
| SCHEMBL17541540 | 0.82 | OGA (0.43) | OGAALDH1A1HSD17B10FFAR1TRPM5 | |
| SCHEMBL30644654 | 0.82 | OGA (0.43) | OGAALDH1A1HSD17B10FFAR1TRPM5 | |
| SCHEMBL21123818 | 0.82 | OGA (0.43) | OGAALDH1A1HSD17B10FFAR1TRPM5 | |
| SCHEMBL17541608 | 0.82 | FFAR1 (0.44) | OGAALDH1A1HSD17B10FFAR1TRPM5 | |
| SCHEMBL2041345 | 0.82 | OGA (0.43) | OGAALDH1A1HSD17B10FFAR1TRPM5 | |
| Hydrochloric Acid SCHEMBL3929197 | 0.81 | OGA (0.43) | OGAALDH1A1HSD17B10FFAR1TRPM5 | |
| SCHEMBL25490381 | 0.79 | OGA (0.42) | OGAALDH1A1HSD17B10FFAR1TRPM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220220111-A1 | 1,8-NAPHTHYRIDINONE COMPOUNDS AND USES THEREOF | NUVATION BIO OPERATING COMPANY INC (US) | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220220111-A1 | 1,8-NAPHTHYRIDINONE COMPOUNDS AND USES THEREOF | NME1, ADORA2A, GPR68 | OGA 2912/4885ALDH1A1 1543/4885HSD17B10 4334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.