⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15871030 | 0.77 | EP300 (0.42) | — | |
| SCHEMBL2459882 | 0.74 | NPC1 (0.44) | — | |
| SCHEMBL2463732 | 0.72 | POLB (0.43) | — | |
| SCHEMBL2461114 | 0.69 | AOC1 (0.43) | — | |
| SCHEMBL2461115 | 0.69 | AOC1 (0.43) | — | |
| SCHEMBL2462271 | 0.67 | KMT2A (0.47) | — | |
| SCHEMBL2462804 | 0.67 | — | — | |
| SCHEMBL2460093 | 0.67 | RAB9A (0.39) | — | |
| SCHEMBL2460094 | 0.67 | RAB9A (0.39) | — | |
| SCHEMBL15870906 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110237633-A1 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR | 2011-09-29 | — | — | US | disclosed |
| WO-2010068287-A2 | SMALL MOLECULE MODULATORS OF HEPATOCYTE GROWTH FACTOR (SCATTER FACTOR) ACTIVITY | ANGION BIOMEDICA CORP. (US) | 2010-06-17 | — | — | WO | disclosed |