SCHEMBL24618673

SCHEMBL24618673

CN(CCCn1cccc(CCN2C(=O)c3ccccc3C2=O)c1=O)C(=O)OC(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.41
ACHE P22303 5/20 0.38
BCHE P06276 1/20 0.38
GAA P10253 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
PDK2 Q15119 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15996418 0.85 MAOB (0.51) MAOBACHEBCHE
SCHEMBL24618544 0.82 BRD4 (0.42) TDP1
SCHEMBL29792012 0.82 BRD4 (0.42) TDP1
SCHEMBL31439940 0.81 MAOB (0.52) MAOBACHEBCHE
SCHEMBL2399096 0.81 MAOB (0.52) MAOBACHEBCHE
SCHEMBL23728845 0.81 MAOB (0.53) MAOBACHE
SCHEMBL21227666 0.81 ACHE (0.53) MAOBACHEBCHE
SCHEMBL31655718 0.81 ACHE (0.53) MAOBACHEBCHE
SCHEMBL22291527 0.81 ACHE (0.53) MAOBACHEBCHE
SCHEMBL30304462 0.81 ACHE (0.53) MAOBACHEBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022149167-A1 DIAMINOPYRAZOLO[1,5-A]PYRIMIDINE-6-CARBONITRILE COMPOUNDS AS ADENOSINE 2A RECEPTOR AND ADENOSINE 2B RECEPTOR ANTAGONIST BUGWORKS RESEARCH INDIA PVT LTD (IN) 2022-07-14 WO disclosed