SCHEMBL23728845

SCHEMBL23728845

CN(CCCN(C)C(=O)OC(C)(C)C)CCCN1C(=O)c2ccccc2C1=O

nearest known ligand 0.53

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MAOB P27338 7/20 0.53
ACHE P22303 9/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15996418 0.95 MAOB (0.51) MAOBACHE
SCHEMBL31439940 0.91 MAOB (0.52) MAOBACHE
SCHEMBL2399096 0.91 MAOB (0.52) MAOBACHE
SCHEMBL30304462 0.90 ACHE (0.53) MAOBACHE
SCHEMBL21227666 0.90 ACHE (0.53) MAOBACHE
SCHEMBL22291527 0.90 ACHE (0.53) MAOBACHE
SCHEMBL31655718 0.90 ACHE (0.53) MAOBACHE
SCHEMBL14554544 0.87 MAOB (0.49) MAOB
SCHEMBL21997754 0.85 SMN1; SMN2 (0.42) MAOB
SCHEMBL19925980 0.84 MAOB (0.49) MAOBACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119584961-A Methods and compounds for modulating huntington's disease 设计治疗公司 2025-03-07 CN disclosed
EP-4504339-A2 METHODS AND COMPOUNDS FOR MODULATING HUNTINGTON'S DISEASE Design Therapeutics, Inc. (US) 2025-02-12 EP disclosed
US-20240360105-A1 PROCESS FOR POLYAMIDE SYNTHESIS Design Therapeutics, Inc. 2024-10-31 US disclosed
EP-4384506-A1 PROCESS FOR POLYAMIDE SYNTHESIS Design Therapeutics, Inc. (US) 2024-06-19 EP disclosed
US-20240058460-A1 METHODS AND COMPOUNDS FOR MODULATING HUNTINGTON'S DISEASE Design Therapeutics, Inc. 2024-02-22 US disclosed
US-20240050576-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2024-02-15 US disclosed
US-20240042046-A1 METHODS AND COMPOUNDS FOR MODULATING HUNTINGTON'S DISEASE DESIGN THERAPEUTICS INC (US) 2024-02-08 US disclosed
WO-2023192642-A2 METHODS AND COMPOUNDS FOR MODULATING HUNTINGTON'S DISEASE Design Therapeutics, Inc. (US) 2023-10-05 WO disclosed
US-20230149550-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. 2023-05-18 US disclosed
CN-115768765-A Methods and compounds for treating genetic diseases 设计治疗公司 2023-03-07 CN disclosed
WO-2023014793-A1 PROCESS FOR POLYAMIDE SYNTHESIS Design Therapeutics, Inc. (US) 2023-02-09 WO disclosed
EP-4100404-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. (US) 2022-12-14 EP disclosed
WO-2021158707-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE Design Therapeutics, Inc. (US) 2021-08-12 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230149550-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE DMPK, DTYMK, MYCBP MAOB 1592/4885ACHE 4656/4885
US-20240058460-A1 METHODS AND COMPOUNDS FOR MODULATING HUNTINGTON'S DISEASE HTT, TARDBP, HYPK MAOB 1558/4885ACHE 1858/4885
US-20240360105-A1 PROCESS FOR POLYAMIDE SYNTHESIS POLI, POLR2A, POLR2B MAOB 2295/4885ACHE 4873/4885
US-20240042046-A1 METHODS AND COMPOUNDS FOR MODULATING HUNTINGTON'S DISEASE HTT, TARDBP, HYPK MAOB 1558/4885ACHE 1858/4885
US-20240050576-A1 METHODS AND COMPOUNDS FOR THE TREATMENT OF GENETIC DISEASE ZFX, GRN, F13B MAOB 797/4885ACHE 4472/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.