Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24619751 | 0.88 | GAA (0.46) | KMT2AMEN1KDM4EMAPTTDP1 | |
| SCHEMBL24619192 | 0.81 | PRMT5 (0.47) | KMT2AMEN1THRBMAPTATM | |
| SCHEMBL24482792 | 0.80 | KMT2A (0.39) | KMT2AMEN1THRBKDM4EMAPT | |
| SCHEMBL24619284 | 0.78 | LIPG (0.37) | KMT2AMEN1THRBLIPGGAA | |
| SCHEMBL16854241 | 0.74 | PIK3CD (0.45) | POLB | |
| SCHEMBL8076472 | 0.74 | LIPG (0.47) | LIPG | |
| SCHEMBL24619159 | 0.74 | AAK1 (0.42) | KMT2AMEN1L3MBTL1 | |
| SCHEMBL5111381 | 0.71 | AAK1 (0.47) | KMT2AMEN1THRBKDM4EMAPT | |
| SCHEMBL11901319 | 0.71 | GAA (0.41) | KMT2AMEN1THRBMAPTPOLB | |
| SCHEMBL23205455 | 0.70 | GPR139 (0.48) | KMT2AL3MBTL1POLBATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149057-A1 | CDK INHIBITORS | RHIZEN PHARMACEUTICALS AG (CH) | 2022-07-14 | — | — | WO | disclosed |