Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.57 |
| ▸ | THRB | P10828 | 2/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24619752 | 1.00 | LMNA (0.57) | LMNATHRBRXFP1MAPTSMN1; SMN2 | |
| SCHEMBL24619246 | 0.91 | LMNA (0.58) | LMNATHRBRXFP1MAPTSMN1; SMN2 | |
| SCHEMBL24741290 | 0.86 | LMNA (0.67) | LMNATHRBRXFP1MAPTTP53 | |
| SCHEMBL24619503 | 0.85 | LMNA (0.56) | LMNATHRBRXFP1MAPTSMN1; SMN2 | |
| SCHEMBL24619717 | 0.84 | LMNA (0.57) | LMNATHRBRXFP1MAPTSMN1; SMN2 | |
| SCHEMBL24619716 | 0.84 | LMNA (0.57) | LMNATHRBRXFP1MAPTSMN1; SMN2 | |
| SCHEMBL24619789 | 0.83 | LMNA (0.56) | LMNATHRBRXFP1MAPTSMN1; SMN2 | |
| SCHEMBL24619287 | 0.83 | THRB (0.56) | LMNATHRBRXFP1MAPTTP53 | |
| SCHEMBL24619462 | 0.83 | LMNA (0.58) | LMNATHRBRXFP1MAPTSMN1; SMN2 | |
| Formic Acid SCHEMBL29925099 | 0.81 | LMNA (0.54) | LMNATHRBRXFP1MAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150316-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2022-07-14 | — | — | WO | disclosed |