Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 4/20 | 0.33 |
| ▸ | GAA | P10253 | 4/20 | 0.33 |
| ▸ | SI | P14410 | 4/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2460915 | 0.91 | MGAM (0.34) | CHRM1KDM4EMGAMGAASI | |
| SCHEMBL2488207 | 0.86 | CHRM1 (0.41) | CHRM1MAOBKDM4ETP53CYP3A4 | |
| SCHEMBL2491673 | 0.85 | CHRM1 (0.42) | CHRM1MAOBKDM4ETP53CYP3A4 | |
| SCHEMBL15472265 | 0.84 | CHRM1 (0.43) | CHRM1MAOBKDM4ETP53CYP3A4 | |
| SCHEMBL1135918 | 0.84 | CHRM1 (0.40) | CHRM1MAOBKDM4ECYP3A4HSD17B10 | |
| SCHEMBL1136185 | 0.83 | CHRM1 (0.41) | CHRM1MAOBKDM4ECYP3A4HSD17B10 | |
| SCHEMBL13560282 | 0.83 | CHRM1 (0.39) | CHRM1MAOBKDM4ECYP3A4HSD17B10 | |
| SCHEMBL3663892 | 0.83 | CHRM1 (0.39) | CHRM1MAOBKDM4ECYP3A4HSD17B10 | |
| SCHEMBL2581807 | 0.83 | CHRM1 (0.45) | CHRM1MAOBCLK1RAB9APTGDR2 | |
| SCHEMBL27844048 | 0.83 | MET (0.33) | MAOBMGAMGAASIMGAM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364298-A1 | Quinolone compound and pharmaceutical composition | Otsuka Pharmaceutical Co., Ltd. (JP) | 2011-09-14 | — | — | EP | disclosed |
| WO-2010064735-A1 | QUINOLONE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2010-06-10 | — | — | WO | disclosed |