Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 6/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24619399 | 0.80 | LMNA (0.58) | APPLMNARXFP1MAPTTP53 | |
| SCHEMBL30086073 | 0.80 | LMNA (0.58) | APPLMNARXFP1MAPTTP53 | |
| SCHEMBL24619206 | 0.79 | LMNA (0.55) | APPLMNARXFP1MAPTTP53 | |
| SCHEMBL24619304 | 0.77 | LMNA (0.57) | APPLMNARXFP1MAPTTP53 | |
| SCHEMBL29925500 | 0.76 | MAPT (0.75) | LMNAMAPTTP53SMN1; SMN2THRB | |
| SCHEMBL29925146 | 0.76 | MAPT (0.75) | LMNAMAPTTP53SMN1; SMN2THRB | |
| SCHEMBL29925235 | 0.76 | MAPT (0.75) | LMNAMAPTTP53SMN1; SMN2THRB | |
| SCHEMBL24619319 | 0.76 | MAPT (0.75) | LMNAMAPTTP53SMN1; SMN2THRB | |
| SCHEMBL24619321 | 0.76 | MAPT (0.75) | LMNAMAPTTP53SMN1; SMN2THRB | |
| SCHEMBL24619295 | 0.75 | LMNA (0.46) | APPLMNARXFP1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150316-A1 | C-MYC MRNA TRANSLATION MODULATORS AND USES THEREOF IN THE TREATMENT OF CANCER | ANIMA BIOTECH INC. (US) | 2022-07-14 | — | — | WO | disclosed |