Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 14/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | ESRRB | O95718 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.46 |
| ▸ | ESRRA | P11474 | 1/20 | 0.46 |
| ▸ | ESRRG | P62508 | 1/20 | 0.46 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26847269 | 0.85 | SMN1; SMN2 (0.53) | GPR119LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5231091 | 0.81 | MAPT (0.61) | GPR119LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL26846050 | 0.79 | OPRD1 (0.48) | LMNAMAPTALDH1A1 | |
| SCHEMBL5573222 | 0.79 | MAPT (0.76) | GPR119LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL26846190 | 0.79 | GPR119 (0.47) | GPR119LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL7662288 | 0.78 | MAPT (0.61) | GPR119LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL4940981 | 0.78 | MAPT (0.61) | GPR119LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL5080444 | 0.78 | MAPT (0.57) | GPR119LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL24619971 | 0.77 | KMT2A (0.68) | GPR119LMNAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL21750394 | 0.77 | MAPT (0.56) | GPR119LMNAMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4279476-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-22 | — | — | EP | disclosed |
| WO-2022149618-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | 中外製薬株式会社 | 2022-07-14 | — | — | WO | disclosed |