Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 5/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | GPR119 | Q8TDV5 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ESRRB | O95718 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ESRRA | P11474 | 1/20 | 0.48 |
| ▸ | ESRRG | P62508 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24619971 | 0.86 | KMT2A (0.68) | SMN1; SMN2KMT2AMEN1CYP2C19HTT | |
| SCHEMBL20423694 | 0.84 | KMT2A (0.68) | SMN1; SMN2KMT2AMEN1CYP2C19HTT | |
| SCHEMBL29080216 | 0.84 | KMT2A (0.59) | SMN1; SMN2KMT2AMEN1CYP2C19HTT | |
| SCHEMBL12720262 | 0.83 | KMT2A (0.64) | SMN1; SMN2KMT2AMEN1CYP2C19HTT | |
| SCHEMBL18667883 | 0.83 | SMN1; SMN2 (0.67) | SMN1; SMN2KMT2AMEN1CYP2C19HTT | |
| SCHEMBL26681993 | 0.82 | SMN1; SMN2 (0.82) | SMN1; SMN2KMT2AMEN1CYP2C19HTT | |
| SCHEMBL2388387 | 0.81 | MAPT (0.62) | SMN1; SMN2KMT2AMEN1CYP2C19HTT | |
| SCHEMBL5573222 | 0.81 | MAPT (0.76) | SMN1; SMN2KMT2AMEN1CYP2C19HTT | |
| SCHEMBL29803251 | 0.81 | MAPT (0.69) | SMN1; SMN2KMT2AMEN1CYP2C19HTT | |
| SCHEMBL28516401 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2KMT2AMEN1CYP2C19HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149618-A1 | METHOD FOR ALKYLATING ACIDIC FUNCTIONAL GROUP | 中外製薬株式会社 | 2022-07-14 | — | — | WO | disclosed |