Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.31 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.31 |
| ▸ | SORD | Q00796 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26141099 | 0.84 | HTR3A (0.33) | CHRNA7HTR3A | |
| SCHEMBL26141058 | 0.80 | IDH1 (0.33) | CHRNA7HTR3A | |
| SCHEMBL13782273 | 0.75 | ALOX15 (0.33) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL22545193 | 0.70 | CYP1A2 (0.41) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL24620396 | 0.70 | SYK (0.34) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL15888817 | 0.68 | HDAC8 (0.30) | — | |
| SCHEMBL10274928 | 0.68 | CHRNA7 (0.47) | CHRNA7HTR3ASORD | |
| SCHEMBL20892195 | 0.68 | CHRNA7 (0.35) | CHRNA7 | |
| SCHEMBL1106508 | 0.67 | HRH4 (0.38) | CHRNA7HTR3ASORD | |
| SCHEMBL807734 | 0.67 | GRM4 (0.37) | CHRNA7HTR3ASORD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220220115-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | SAGARD HOLDINGS MANAGER LP, AS ADMINISTRATIVE AGENT (CA) | 2022-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220220115-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | WEE1, WEE2, NME1 | CHRNA7 4881/4885HTR3A 4004/4885PIK3CD 1284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.