SCHEMBL24620599

SCHEMBL24620599

Oc1ccc2ccc3c(c2c1)C=CC(c1ccc(N2CCCC2)cc1)(c1ccc(N2CCCC2)cc1)O3

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 2/20 0.34
ALK Q9UM73 1/20 0.34
CTSL P07711 2/20 0.32
CTSB P07858 2/20 0.32
APP P05067 1/20 0.31
ESR1 P03372 2/20 0.31
ESR2 Q92731 2/20 0.31
HTR5A P47898 1/20 0.31
TERT O14746 2/20 0.31
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
HSD17B1 P14061 1/20 0.30
HSD17B2 P37059 1/20 0.30
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
PKM P14618 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24620639 0.85 SMN1; SMN2 (0.42) KDM4EALDH1A1MAPT
SCHEMBL24620629 0.84 SMN1; SMN2 (0.42) TERTKDM4EALDH1A1MAPT
SCHEMBL24620628 0.84 APP (0.38) APPKDM4EALDH1A1MAPTPKM
SCHEMBL24620601 0.82 ALDH1A1 (0.33) TERTKDM4EALDH1A1MAPT
SCHEMBL21877250 0.81 SMN1; SMN2 (0.34) HTR5ATERTKDM4EALDH1A1MAPT
SCHEMBL4673163 0.80 HTT (0.35) TERT
SCHEMBL4674836 0.80 HTT (0.35) TERT
SCHEMBL4671088 0.80 HTT (0.35) TERT
SCHEMBL25106834 0.80 MEN1 (0.33) TERTKDM4EMAPT
SCHEMBL6321380 0.80 HTT (0.35) TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022148752-A9 PHOTOCHROMIC DYES AND POLYMERIC MATRIX FOR AN EFFICIENT DIMMING FILM Sony Group Corporation (JP) 2023-08-03 WO disclosed
WO-2022148752-A2 PHOTOCHROMIC DYES AND POLYMERIC MATRIX FOR AN EFFICIENT DIMMING FILM Sony Group Corporation (JP) 2022-07-14 WO disclosed