SCHEMBL24622658

SCHEMBL24622658

c1ccc(-c2nc(-c3ccccc3-c3ccccc3)nc(-c3c4ccccc4c(-c4ccc5c(c4)C4(c6ccccc6-5)C5CC6CC(C5)CC4C6)c4ccccc34)n2)cc1

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.33
PDE7A Q13946 2/20 0.32
PDE7B Q9NP56 2/20 0.32
HSD11B1 P28845 1/20 0.31
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
KMT2A Q03164 1/20 0.30
PDE4A P27815 1/20 0.30
PDE4B Q07343 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30
PDE3B Q13370 1/20 0.30
PDE3A Q14432 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24622705 0.99 HSD11B1 (0.32) HTTPDE7APDE7BHSD11B1
SCHEMBL24622683 0.96 HTT (0.35) HTTHSD11B1MEN1ALDH1A1MAPT
SCHEMBL24622660 0.95 HTT (0.34) HTTHSD11B1MEN1ALDH1A1MAPT
SCHEMBL24622703 0.95 HTT (0.34) HTTHSD11B1MEN1ALDH1A1MAPT
SCHEMBL24622891 0.92 PDK2 (0.34) HTTPDE7APDE7BHSD11B1MEN1
SCHEMBL23626217 0.91 PDE7A (0.32) PDE7APDE7BPDE4APDE4BPDE4C
SCHEMBL24622659 0.91 PDK2 (0.33) HTTPDE7APDE7BHSD11B1
SCHEMBL24622729 0.90 PDK2 (0.34) HTTPDE7APDE7BHSD11B1
SCHEMBL24622682 0.89 HSD11B1 (0.33) HTTHSD11B1MEN1ALDH1A1MAPT
SCHEMBL24608932 0.87 PDK2 (0.35) HTTHSD11B1MEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220220049-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2022-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220220049-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS HCN2, EPCAM, EFNA1 HTT 258/4885PDE7A 1184/4885PDE7B 2330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.