SCHEMBL24622669

SCHEMBL24622669

c1ccc(-c2cc(-c3ccccc3)nc(-c3c4ccccc4c(-c4ccc5c(c4)-c4ccccc4C54C5CC6CC(C5)CC4C6)c4ccccc34)c2)cc1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.32
HSD11B1 P28845 1/20 0.31
MYC P01106 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
CYP19A1 P11511 1/20 0.30
DHODH Q02127 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23605913 0.87 PDK2 (0.34) PDK2MYCMEN1KMT2ADHODH
SCHEMBL24622553 0.86 MEN1 (0.36) PDK2HSD11B1MEN1KMT2A
SCHEMBL24622682 0.84 HSD11B1 (0.33) PDK2HSD11B1MEN1KMT2ADHODH
SCHEMBL24617939 0.81 MEN1 (0.37) PDK2MEN1KMT2A
SCHEMBL24622660 0.81 HTT (0.34) PDK2HSD11B1MEN1KMT2A
SCHEMBL24622703 0.81 HTT (0.34) PDK2HSD11B1MEN1KMT2A
SCHEMBL24617937 0.81 MEN1 (0.39) PDK2MEN1KMT2A
SCHEMBL25626139 0.80 HSD11B1 (0.34) PDK2HSD11B1
SCHEMBL24622683 0.80 HTT (0.35) PDK2HSD11B1MEN1KMT2A
SCHEMBL23626260 0.79 PDK2 (0.36) PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220220049-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2022-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220220049-A1 ORGANIC COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE AND ELECTRONIC APPARATUS HCN2, EPCAM, EFNA1 PDK2 611/4885HSD11B1 2209/4885MYC 664/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.