Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 2/20 | 0.37 |
| ▸ | TCF7L2 | Q9NQB0 | 2/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.37 |
| ▸ | CDK2 | P24941 | 6/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.36 |
| ▸ | CCNA1 | P78396 | 4/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.36 |
| ▸ | CLK2 | P49760 | 2/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.36 |
| ▸ | MAP4K2 | Q12851 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | PAK4 | O96013 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29923111 | 0.87 | FGFR1 (0.41) | FGFR1FGFR2CDK2CCNA2CCNA1 | |
| SCHEMBL3227639 | 0.87 | FGFR1 (0.41) | FGFR1FGFR2CDK2CCNA2CCNA1 | |
| SCHEMBL13099704 | 0.85 | CDK2 (0.42) | FGFR1FGFR2CDK2CCNA2CCNA1 | |
| SCHEMBL7954698 | 0.82 | FGFR1 (0.41) | FGFR1FGFR2CDK7HDAC6MAPT | |
| SCHEMBL13099651 | 0.78 | CDK1 (0.40) | CDK2CDK1KMT2A | |
| SCHEMBL3233985 | 0.78 | RAB9A (0.42) | FGFR1FGFR2CDK2CCNA2CCNA1 | |
| SCHEMBL8043069 | 0.78 | GSK3B (0.52) | CDK2MAP4K4CLK2CDK5MAP4K2 | |
| SCHEMBL8041157 | 0.77 | CDK2 (0.40) | CDK2CCNA2CCNA1MAP4K4CLK2 | |
| SCHEMBL13099781 | 0.77 | DDR2 (0.42) | FGFR1NTRK1CDK2CCNA2CCNA1 | |
| SCHEMBL8031088 | 0.77 | CDK2 (0.41) | FGFR1CDK2CCNA2CCNA1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022148822-A1 | USP5 BINDING SURVIVAL-TARGETING CHIMERIC (SURTAC) MOLECULES & USES THEREOF | LOCKI THERAPEUTICS LIMITED (GB) | 2022-07-14 | — | — | WO | disclosed |