Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHD1 | Q9H4M9 | 7/20 | 0.50 |
| ▸ | SLC40A1 | Q9NP59 | 5/20 | 0.46 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.45 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | TCF4 | P15884 | 1/20 | 0.40 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.39 |
| ▸ | ITGAV | P06756 | 1/20 | 0.39 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.39 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.39 |
| ▸ | BIRC3 | Q13489 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24627031 | 0.99 | EHD1 (0.50) | EHD1SLC40A1NMUR2NMUR1CTSG | |
| SCHEMBL24627252 | 0.97 | EHD1 (0.50) | EHD1SLC40A1NMUR2NMUR1CTSG | |
| SCHEMBL24626997 | 0.90 | EHD1 (0.47) | EHD1SLC40A1NMUR2NMUR1CTSG | |
| SCHEMBL24627222 | 0.90 | EHD1 (0.44) | EHD1SLC40A1NMUR2NMUR1CTSG | |
| SCHEMBL24626969 | 0.90 | EHD1 (0.44) | EHD1SLC40A1NMUR2NMUR1CTSG | |
| SCHEMBL24627075 | 0.88 | EHD1 (0.43) | EHD1SLC40A1NMUR2NMUR1CTSG | |
| SCHEMBL24626991 | 0.86 | EHD1 (0.58) | EHD1SLC40A1MEN1HDAC4TCF4 | |
| SCHEMBL22887739 | 0.85 | SLC40A1 (0.58) | EHD1SLC40A1NMUR2NMUR1TCF4 | |
| SCHEMBL24627335 | 0.84 | EHD1 (0.53) | EHD1SLC40A1MEN1HDAC4TCF4 | |
| SCHEMBL24627014 | 0.83 | EHD1 (0.47) | EHD1SLC40A1NMUR2NMUR1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022148843-A1 | COMPOUNDS COMPRISING A FIBROBLAST ACTIVATION PROTEIN LIGAND AND USE THEREOF | 3B PHARMACEUTICALS GMBH (DE) | 2022-07-14 | — | — | WO | disclosed |