Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.41 |
| ▸ | QDPR | P09417 | 2/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13974630 | 0.98 | SLC6A4 (0.42) | SLC6A4SLC22A2SLC22A1SLC22A3QDPR | |
| Bromide SCHEMBL918125 | 0.91 | MEN1 (0.38) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL1226951 | 0.89 | MEN1 (0.39) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL12905322 | 0.88 | MEN1 (0.43) | SLC6A4SLC22A2SLC22A1SLC22A3QDPR | |
| Hydrochloric Acid SCHEMBL210855 | 0.87 | MEN1 (0.38) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL22953518 | 0.85 | MEN1 (0.49) | SLC6A4SLC22A2SLC22A1SLC22A3MEN1 | |
| SCHEMBL22953514 | 0.85 | MEN1 (0.49) | SLC6A4SLC22A2SLC22A1SLC22A3MEN1 | |
| SCHEMBL9889761 | 0.84 | MEN1 (0.41) | MEN1TP53CYP1A2CYP2D6MAPT | |
| Hydrochloric Acid SCHEMBL3364505 | 0.82 | MEN1 (0.40) | MEN1TP53CYP1A2CYP2D6MAPT | |
| SCHEMBL29201320 | 0.82 | MEN1 (0.40) | MEN1TP53CYP1A2CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8999430-B2 | Method of manufacturing display element | KONICA MINOLTA HOLDINGS, INC. (JP) | 2015-04-07 | — | — | US | disclosed |
| EP-2149816-B1 | METHOD OF MANUFACTURING AN ELECTROCHROMIC DISPLAY ELEMENT | KONICA MINOLTA HOLDINGS INC (JP) | 2014-05-07 | — | — | EP | disclosed |
| US-8014056-B2 | Display element and method of driving the same | KONICA MINOLTA HOLDINGS, INC. (JP) | 2011-09-06 | — | — | US | disclosed |
| US-20100166946-A1 | METHOD OF MANUFACTURING DISPLAY ELEMENT | KONICA MINOLTA HOLDINGS, INC. (JP) | 2010-07-01 | — | — | US | disclosed |
| US-20100091353-A1 | DISPLAY ELEMENT AND METHOD OF DRIVING THE SAME | KONICA MINOLTA HOLDINGS, INC. (JP) | 2010-04-15 | — | — | US | disclosed |
| EP-2149816-A1 | METHOD FOR PRODUCTION OF DISPLAY ELEMENT | Konica Minolta Holdings, Inc. (JP) | 2010-02-03 | — | — | EP | disclosed |
| EP-2096490-A1 | DISPLAY ELEMENT AND METHOD OF DRIVING THE SAME | Konica Minolta Holdings, Inc. (JP) | 2009-09-02 | — | — | EP | disclosed |