Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHKA known ✓ | P35790 | 1/20 | 0.32 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.35 |
| ▸ | TYMS | P04818 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1226951 | 0.98 | MEN1 (0.39) | MEN1KMT2ATP53CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL210855 | 0.96 | MEN1 (0.38) | MEN1KMT2ATP53CYP1A2CYP2D6 | |
| Bromide SCHEMBL2462794 | 0.91 | SLC6A4 (0.41) | MEN1KMT2ATP53CYP1A2CYP2D6 | |
| SCHEMBL9889761 | 0.88 | MEN1 (0.41) | MEN1KMT2ATP53CYP1A2CYP2D6 | |
| SCHEMBL13974630 | 0.88 | SLC6A4 (0.42) | MEN1KMT2ATP53CYP1A2CYP2D6 | |
| Bromide SCHEMBL31354579 | 0.88 | MEN1 (0.44) | MEN1KMT2ATP53CYP1A2CYP2D6 | |
| Bromide SCHEMBL5586402 | 0.88 | PABPC1 (0.39) | MEN1KMT2AMAPTLMNA | |
| Hydrochloric Acid SCHEMBL3364505 | 0.87 | MEN1 (0.40) | MEN1KMT2ATP53CYP1A2CYP2D6 | |
| SCHEMBL29201320 | 0.87 | MEN1 (0.40) | MEN1KMT2ATP53CYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL193627 | 0.85 | PABPC1 (0.40) | MAPTLMNAGGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8437067-B2 | Electrochemical display element | KONICA MINOLTA HOLDINGS, INC. (JP) | 2013-05-07 | — | — | US | disclosed |
| EP-1004143-B1 | CHARGE GENERATORS IN HETEROLAMELLAR MULTILAYER THIN FILMS | UNIV SOUTHERN CALIFORNIA (US) | 2012-09-05 | — | — | EP | disclosed |
| EP-2287937-A2 | Charge generators in heterolamellar multilayer thin films | The University of Southern California (US) | 2011-02-23 | — | — | EP | disclosed |
| US-20110013261-A1 | ELECTROCHEMICAL DISPLAY ELEMENT | KONICA MINOLTA HOLDINGS, INC. (JP) | 2011-01-20 | — | — | US | disclosed |
| US-20100097684-A1 | DISPLAY ELEMENT | KONICA MINOLTA HOLDINGS, INC. (JP) | 2010-04-22 | — | — | US | disclosed |
| EP-0871985-B1 | HETEROLAMELLAR PHOTOVOLTAIC FILMS | UNIV PRINCETON (US) | 2009-08-19 | — | — | EP | disclosed |
| EP-1386884-B1 | Process for production of hydrogen peroxide by direct synthesis from hydrogen and oxygen | UNIV PRINCETON (US) | 2007-03-07 | — | — | EP | disclosed |
| EP-1004143-A4 | CHARGE GENERATORS IN HETEROLAMELLAR MULTILAYER THIN FILMS | UNIV SOUTHERN CALIFORNIA (US) | 2006-04-12 | — | — | EP | disclosed |
| EP-1394185-A1 | Derivative of polyvinylpyridine | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2004-03-03 | — | — | EP | disclosed |
| EP-1386884-A1 | Electron acceptor compositions on polymer templates and catalytic production of hydrogen peroxide | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2004-02-04 | — | — | EP | disclosed |
| EP-0871985-A4 | HETEROLAMELLAR PHOTOVOLTAIC FILMS | UNIV PRINCETON (US) | 1999-06-09 | — | — | EP | disclosed |
| US-5906892-A | GROUP VIII METAL COMPLEX ON SUPPORT | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1999-05-25 | — | — | US | disclosed |
| WO-1999003154-A1 | CHARGE GENERATORS IN HETEROLAMELLAR MULTILAYER THIN FILMS | UNIVERSITY OF SOUTHERN CALIFORNIA (US) | 1999-01-21 | — | — | WO | disclosed |
| EP-0871985-A1 | HETEROLAMELLAR PHOTOVOLTAIC FILMS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1998-10-21 | — | — | EP | disclosed |
| US-5695890-A | PHOTOELECTRODE COMPRISING CHARGE TRANSFER COMPLEX; REDOX CATALYSTS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1997-12-09 | — | — | US | disclosed |
| WO-1997024775-A1 | HETEROLAMELLAR PHOTOVOLTAIC FILMS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1997-07-10 | — | — | WO | disclosed |
| EP-0713492-A1 | ELECTRON ACCEPTOR COMPOSITIONS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1996-05-29 | — | — | EP | disclosed |
| US-5500297-A | PHOTOINDUCED CHARGE SEPARATION, ORGANIC PILLARS, REPEATING CATIONIC CENTERS AND METAL PHOSPHONATES WITH ENTRAPPED COLLOIDAL PARTICLES OF PALLADIUM OR PLATINUM | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1996-03-19 | — | — | US | disclosed |
| US-5480629-A | TREATING AN AQUEOUS SUSPENSION OF CATALYST WITH OXYGEN AND HYDROGEN SOURCES, SEPARATING THE CATALYST AND ISOLATING HYDROGEN PEROXIDE | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1996-01-02 | — | — | US | disclosed |
| WO-1995004743-A1 | ELECTRON ACCEPTOR COMPOSITIONS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 1995-02-16 | — | — | WO | disclosed |