SCHEMBL24628016

SCHEMBL24628016

c1ccc(-c2nc(-c3cccc(-c4ccc5c6ccccc6c6cccc7oc4c5c76)c3)nc3c2oc2ccccc23)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 11/20 0.43
ALDH1A1 P00352 6/20 0.42
TSHR P16473 5/20 0.42
KDM4E B2RXH2 3/20 0.42
POLB P06746 2/20 0.42
HPGD P15428 1/20 0.42
NPSR1 Q6W5P4 3/20 0.42
KMT2A Q03164 6/20 0.41
LMNA P02545 4/20 0.41
HSD17B10 Q99714 3/20 0.41
USP2 O75604 1/20 0.41
HTT P42858 1/20 0.41
MEN1 O00255 5/20 0.40
MAPK1 P28482 2/20 0.40
CYP1A2 P05177 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
GAA P10253 1/20 0.39
ALOX12 P18054 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24628825 0.97 MAPT (0.45) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL24628266 0.92 MAPT (0.42) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL24628021 0.92 ALDH1A1 (0.44) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL24628846 0.89 MAPT (0.44) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL24628827 0.89 ALDH1A1 (0.42) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL18017660 0.88 MAPT (0.52) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL24627937 0.87 MAPT (0.42) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL24628848 0.87 MAPT (0.41) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL18852965 0.87 ALOX5 (0.50) MAPTALDH1A1TSHRKDM4EPOLB
SCHEMBL24628546 0.86 ALOX5 (0.39) MAPTALDH1A1TSHRKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022148717-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2022-07-14 WO disclosed