Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.56 |
| ▸ | F2R | P25116 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | PARP1 | P09874 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.55 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.53 |
| ▸ | GRM5 | P41594 | 1/20 | 0.53 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | BLK | P51451 | 1/20 | 0.52 |
| ▸ | BTK | Q06187 | 1/20 | 0.52 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26815558 | 0.91 | MEN1 (0.65) | NPC1RAB9ASMN1; SMN2NR1H4F2R | |
| SCHEMBL12561353 | 0.84 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2NR1H4F2R | |
| SCHEMBL27760395 | 0.81 | PTPN1 (0.76) | NPC1RAB9ASMN1; SMN2NR1H4F2R | |
| SCHEMBL18152289 | 0.81 | MEN1 (0.73) | NPC1RAB9ASMN1; SMN2NR1H4F2R | |
| SCHEMBL15122844 | 0.80 | HDAC8 (0.66) | NPC1RAB9ASMN1; SMN2NR1H4KMT2A | |
| SCHEMBL14043612 | 0.80 | NPC1 (0.75) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL2025738 | 0.79 | NR1H4 (0.72) | NPC1RAB9ASMN1; SMN2NR1H4F2R | |
| SCHEMBL2497760 | 0.79 | MEN1 (0.68) | RAB9AKMT2AMEN1KCNK3KCNK9 | |
| SCHEMBL6451496 | 0.79 | KMT2A (0.73) | NPC1RAB9ASMN1; SMN2NR1H4F2R | |
| SCHEMBL13838142 | 0.78 | RAB9A (0.53) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022149617-A1 | COMPOUND LIBRARY | 中外製薬株式会社 | 2022-07-14 | — | — | WO | disclosed |