Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | RAF1 | P04049 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | BRAF | P15056 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24629178 | 0.91 | NPC1 (0.57) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL26815735 | 0.88 | NPC1 (0.59) | MEN1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL26839911 | 0.83 | MEN1 (0.62) | MEN1KMT2AKEAP1NFE2L2NPC1 | |
| SCHEMBL27984049 | 0.78 | MEN1 (0.74) | MEN1KMT2AKEAP1NFE2L2NPC1 | |
| SCHEMBL15122844 | 0.77 | HDAC8 (0.66) | MEN1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL2497760 | 0.76 | MEN1 (0.68) | MEN1KMT2ARAB9AALDH1A1MAPT | |
| SCHEMBL12561353 | 0.75 | NPC1 (0.64) | MEN1KMT2ANPC1RAB9ATP53 | |
| SCHEMBL13838142 | 0.75 | RAB9A (0.53) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL27760395 | 0.75 | PTPN1 (0.76) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6781288 | 0.74 | DEGS1 (0.69) | MEN1KMT2ANPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4276092-A1 | COMPOUND LIBRARY | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2023-11-15 | — | — | EP | disclosed |