SCHEMBL24629290

SCHEMBL24629290

Oc1cccc2[nH]cc(/C=N/Nc3ccc(F)cc3)c12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SENP7 Q9BQF6 8/20 0.64
▸ SENP8 Q96LD8 6/20 0.64
▸ SENP6 Q9GZR1 6/20 0.64
▸ CASP3 P42574 4/20 0.48
▸ GAA P10253 7/20 0.47
▸ KLF5 Q13887 1/20 0.47
▸ KMT2A Q03164 10/20 0.47
▸ MEN1 O00255 9/20 0.47
▸ MAPT P10636 6/20 0.47
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ ALDH1A1 P00352 4/20 0.44
▸ HPGD P15428 1/20 0.44
▸ GFER P55789 1/20 0.44
▸ PSMD14 O00487 1/20 0.44
▸ TLR9 Q9NR96 1/20 0.44
▸ POLB P06746 2/20 0.43
▸ CCR6 P51684 1/20 0.43
▸ HTT P42858 3/20 0.43
▸ NFKB1 P19838 1/20 0.43
▸ NFKB2 Q00653 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27135043 1.00 SENP7 (0.64) SENP7SENP8SENP6CASP3GAA
SCHEMBL27124610 0.88 SENP7 (0.63) SENP7SENP8SENP6CASP3GAA
SCHEMBL24629104 0.88 SENP7 (0.63) SENP7SENP8SENP6CASP3GAA
SCHEMBL24629289 0.87 SENP7 (0.49) SENP7SENP8SENP6CASP3GAA
SCHEMBL27135592 0.87 SENP7 (0.49) SENP7SENP8SENP6CASP3GAA
SCHEMBL1132833 0.79 GAA (0.64) SENP7SENP8SENP6CASP3GAA
SCHEMBL1132832 0.79 GAA (0.64) SENP7SENP8SENP6CASP3GAA
SCHEMBL24629304 0.77 SENP7 (0.58) SENP7SENP8SENP6CASP3GAA
SCHEMBL27125066 0.77 SENP7 (0.58) SENP7SENP8SENP6CASP3GAA
SCHEMBL24629182 0.75 SENP7 (0.49) SENP7SENP8SENP6CASP3GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240010619-A1 SMALL MOLECULES WITH ANTIBACTERIAL ACTIVITY NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION 2024-01-11 — — US disclosed
WO-2022150468-A1 SMALL MOLECULES WITH ANTIBACTERIAL ACTIVITY NEW MEXICO TECH UNIVERSITY RESEARCH PARK CORPORATION (US) 2022-07-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240010619-A1 SMALL MOLECULES WITH ANTIBACTERIAL ACTIVITY CLPP, MRPL21, TIAL1 SENP7 908/4885SENP8 734/4885SENP6 601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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