SCHEMBL24629359

SCHEMBL24629359

CNC1CCC(N(C)C(C)=O)C1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.34
FASN P49327 6/20 0.33
BCHE P06276 1/20 0.33
DPP4 P27487 3/20 0.31
BTK Q06187 1/20 0.31
DPP8 Q6V1X1 2/20 0.31
DPP9 Q86TI2 1/20 0.31
DPP7 Q9UHL4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26599781 0.88 DPP4 (0.35) ACHEDPP4BTKDPP8DPP9
SCHEMBL17207644 0.88 DPP4 (0.35) ACHEDPP4BTKDPP8DPP9
SCHEMBL26599785 0.88 DPP4 (0.35) ACHEDPP4BTKDPP8DPP9
SCHEMBL24629680 0.86 ACHE (0.31) ACHEDPP4DPP8DPP9DPP7
Trifluoroacetic Acid SCHEMBL26599376 0.78 DPP4 (0.33) DPP4BTKDPP8DPP9DPP7
SCHEMBL5506106 0.76
SCHEMBL11982801 0.75 DPP4 (0.34) ACHEDPP4DPP8DPP9DPP7
SCHEMBL19723229 0.74
SCHEMBL17488360 0.74
SCHEMBL17488359 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022150707-A1 FUSED QUADRACYCLIC COMPOUNDS, COMPOSITIONS AND USES THEREOF Tabomedex Biosciences, Inc. (US) 2022-07-14 WO disclosed