Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL26599376

CNC1CCC(N(C)C(C)=O)CC1.O=C(O)C(F)(F)F

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 4/20 0.33
DPP8 Q6V1X1 2/20 0.33
DPP9 Q86TI2 1/20 0.33
DPP7 Q9UHL4 1/20 0.33
ATM Q13315 1/20 0.32
MCHR1 Q99705 1/20 0.31
CCRL2 O00421 1/20 0.31
BTK Q06187 1/20 0.31
NPY5R Q15761 1/20 0.30
HRH4 Q9H3N8 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30
CYP11B2 P19099 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26599781 0.88 DPP4 (0.35) DPP4DPP8DPP9DPP7ATM
SCHEMBL26599785 0.88 DPP4 (0.35) DPP4DPP8DPP9DPP7ATM
SCHEMBL17207644 0.88 DPP4 (0.35) DPP4DPP8DPP9DPP7ATM
SCHEMBL24456071 0.81 MCHR1 (0.33) DPP4DPP8DPP9DPP7MCHR1
SCHEMBL24629359 0.78 ACHE (0.34) DPP4DPP8DPP9DPP7BTK
SCHEMBL4532414 0.77 ATM (0.34) ATMNPY5R
Trifluoroacetic Acid SCHEMBL3006963 0.77 GABRP (0.35) HRH4HRH3
SCHEMBL12849690 0.75 DPP4 (0.35) DPP4DPP8DPP9DPP7ATM
Trifluoroacetic Acid SCHEMBL27702554 0.75 PDK1 (0.43) HRH4HRH3
Trifluoroacetic Acid SCHEMBL29936279 0.75 PDK1 (0.39) DPP4DPP8BTKHRH4HRH3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12454547-B2 Steroidal compositions and methods of treating lipogenic cancers Asteroid Therapeutics (US) 2025-10-28 US disclosed
US-20230340011-A1 STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS Asteroid Therapeutics 2023-10-26 US disclosed
WO-2023205801-A2 STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS Asteroid Therapeutics (US) 2023-10-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12454547-B2 Steroidal compositions and methods of treating lipogenic cancers SREBF1, SREBF2, NR1H3 DPP4 3516/4885DPP8 3541/4885DPP9 3375/4885
US-20230340011-A1 STEROIDAL COMPOSITIONS AND METHODS OF TREATING LIPOGENIC CANCERS SREBF1, SREBF2, NR1H3 DPP4 3516/4885DPP8 3541/4885DPP9 3375/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.