SCHEMBL24629704

SCHEMBL24629704

COC(=O)[C@]1(Sc2ccc(C)cc2)C[C@H](O)[C@@H](NC(C)=O)[C@H]([C@H](O)[C@H](O)CN=[N+]=[N-])O1

nearest known ligand 0.45

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ NEU2 Q9Y3R4 2/20 0.45
▸ NEU4 Q8WWR8 1/20 0.45
▸ NEU3 Q9UQ49 1/20 0.45
▸ NANP Q8TBE9 3/20 0.45
▸ SIGLEC7 Q9Y286 6/20 0.35
▸ CD22 P20273 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16362516 0.93 NEU2 (0.47) NEU2NEU4NEU3NANPSIGLEC7
SCHEMBL24629707 0.93 CD22 (0.41) NEU2NEU4NEU3NANPCD22
SCHEMBL27390999 0.93 NEU2 (0.39) NEU2NEU4NEU3NANPCD22
SCHEMBL29727740 0.92 NEU2 (0.38) NEU2NEU4NEU3NANPCD22
SCHEMBL31695063 0.91 NEU2 (0.37) NEU2NEU4NEU3NANPCD22
SCHEMBL31226018 0.91 NEU2 (0.37) NEU2NEU4NEU3NANPCD22
SCHEMBL24629706 0.88 NEU2 (0.37) NEU2NEU4NEU3NANP
SCHEMBL24630167 0.88 NANP (0.47) NEU2NEU4NEU3NANPSIGLEC7
SCHEMBL29325979 0.88 NANP (0.47) NANPCD22
SCHEMBL31225460 0.84 NEU2 (0.39) NEU2NEU4NEU3CD22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4727537-A2 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF Adaxion Therapeutics, Inc. (US) 2026-04-22 — — EP disclosed
EP-4554622-A2 AUTOANTIGENS ENGINEERED TO SUPPRESS AUTOIMMUNE RESPONSE Osprey Biopharmaceuticals, Inc. (US) 2025-05-21 — — EP disclosed
US-20250127904-A1 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF ADAXION THERAPEUTICS, INC. 2025-04-24 — — US disclosed
WO-2025076427-A1 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF OSPREY BIOPHARMACEUTICALS, INC. (US) 2025-04-10 — — WO disclosed
US-20250064941-A1 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF ADAXION THERAPEUTICS, INC. 2025-02-27 — — US disclosed
WO-2024259007-A2 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF OSPREY BIOPHARMACEUTICALS, INC. (US) 2024-12-19 — — WO disclosed
US-20240238422-A1 Hypoimmunogenic Biotherapeutics ADAXION THERAPEUTICS, INC. 2024-07-18 — — US disclosed
US-20240238422-A1 Hypoimmunogenic Biotherapeutics ADAXION THERAPEUTICS, INC. 2024-07-18 — — US disclosed
US-20240238422-A1 Hypoimmunogenic Biotherapeutics ADAXION THERAPEUTICS, INC. 2024-07-18 — — US disclosed
US-20240216490-A1 Autoantigens Engineered to Suppress Autoimmune Response ADAXION THERAPEUTICS, INC. 2024-07-04 — — US disclosed
US-20240216490-A1 Autoantigens Engineered to Suppress Autoimmune Response ADAXION THERAPEUTICS, INC. 2024-07-04 — — US disclosed
WO-2024015872-A2 AUTOANTIGENS ENGINEERED TO SUPPRESS AUTOIMMUNE RESPONSE OSPREY BIOPHARMACEUTICALS, INC. (US) 2024-01-18 — — WO disclosed
WO-2024015872-A2 AUTOANTIGENS ENGINEERED TO SUPPRESS AUTOIMMUNE RESPONSE OSPREY BIOPHARMACEUTICALS, INC. (US) 2024-01-18 — — WO disclosed
EP-4274582-A1 HYPOIMMUNOGENIC BIOTHERAPEUTICS Osprey Biopharmaceuticals, Inc. (US) 2023-11-15 — — EP disclosed
WO-2022150726-A1 HYPOIMMUNOGENIC BIOTHERAPEUTICS OSPREY BIOPHARMACEUTICALS, INC. (US) 2022-07-14 — — WO disclosed
WO-2022150726-A1 HYPOIMMUNOGENIC BIOTHERAPEUTICS OSPREY BIOPHARMACEUTICALS, INC. (US) 2022-07-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250127904-A1 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF SIGLEC7, SIGLEC9, SELPLG NEU2 24/4885NEU4 25/4885NEU3 15/4885
US-20240216490-A1 Autoantigens Engineered to Suppress Autoimmune Response CD74, MICA, HLA-DRB1 NEU2 1464/4885NEU4 1306/4885NEU3 1553/4885
US-20250064941-A1 SIGLEC LIGANDS, CONJUGATES, AND METHODS OF USE THEREOF SIGLEC7, SIGLEC9, CD2BP2 NEU2 43/4885NEU4 42/4885NEU3 41/4885
US-20240238422-A1 Hypoimmunogenic Biotherapeutics FCGR3B, CD47, IL2 NEU2 429/4885NEU4 1203/4885NEU3 762/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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