Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.41 |
| ▸ | CA2 | P00918 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | PRMT3 | O60678 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL29769076 | 0.98 | CA1 (0.40) | CA1CA2MAPTALDH1A1CYP2C9 | |
| SCHEMBL29769174 | 0.78 | HSD17B10 (0.47) | MAPTALDH1A1CYP2C9KDM4ECYP1A2 | |
| SCHEMBL24629942 | 0.75 | CA1 (0.47) | CA1CA2MAPTALDH1A1CYP2C9 | |
| Hydrochloric Acid SCHEMBL29769147 | 0.74 | CA1 (0.46) | CA1CA2MAPTALDH1A1CYP2C9 | |
| SCHEMBL24629840 | 0.71 | BUB1 (0.36) | MAPTALDH1A1KDM4ETDP1SMN1; SMN2 | |
| SCHEMBL24629914 | 0.70 | ALDH1A1 (0.46) | CA1CA2MAPTALDH1A1CYP2C9 | |
| SCHEMBL7142758 | 0.69 | CA1 (0.47) | CA1CA2MAPTALDH1A1KDM4E | |
| SCHEMBL171873 | 0.67 | POLB (0.70) | CA1CA2MAPTALDH1A1TDP1 | |
| SCHEMBL5969586 | 0.65 | CA1 (0.59) | CA1CA2MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1727275 | 0.65 | TERT (0.72) | MAPTALDH1A1CYP2C9CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150574-A1 | INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE | CORNELL UNIVERSITY (US) | 2022-07-14 | — | — | WO | disclosed |