Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | CA3 | P07451 | 1/20 | 0.30 |
| ▸ | CA9 | Q16790 | 1/20 | 0.30 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5649939 | 0.79 | ERN1 (0.48) | GAAMAPTALDH1A1TSHRKDM4E | |
| SCHEMBL20125032 | 0.78 | ALDH1A1 (0.37) | GAAMAPTALDH1A1TSHRKDM4E | |
| SCHEMBL14404326 | 0.78 | GAA (0.56) | GAAMAPTCA1CA2CA3 | |
| SCHEMBL23564956 | 0.78 | KDM4E (0.41) | GAAMAPTALDH1A1TSHRKDM4E | |
| SCHEMBL348577 | 0.77 | MAPT (0.58) | GAAMAPTALDH1A1TSHRKDM4E | |
| SCHEMBL24447268 | 0.76 | TUBB4A (0.40) | GAAMAPTALDH1A1KDM4EERN1 | |
| SCHEMBL20676095 | 0.75 | ALDH1A1 (0.36) | ALDH1A1TSHRERN1 | |
| SCHEMBL6560116 | 0.74 | MAPT (0.55) | GAAMAPTALDH1A1TSHRKDM4E | |
| SCHEMBL21317861 | 0.71 | CYP3A4 (0.36) | ALDH1A1TSHR | |
| SCHEMBL80048 | 0.70 | KDM4E (0.45) | GAAMAPTALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150574-A1 | INHIBITORS OF MYCOBACTERIUM TUBERCULOSIS LIPOAMIDE DEHYDROGENASE | CORNELL UNIVERSITY (US) | 2022-07-14 | — | — | WO | disclosed |