SCHEMBL24630047

SCHEMBL24630047

[N-]=[N+]=NCCCC[C@H](NC(=O)CCCN=[N+]=[N-])C(=O)NCCOCCOCCOCCOCCC(=O)O

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.48
▸ FOLH1 Q04609 10/20 0.39
▸ ITGB3 P05106 1/20 0.36
▸ ITGA2B P08514 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24630312 0.98 GLP1R (0.47) GLP1RFOLH1
SCHEMBL30998154 0.98 GLP1R (0.47) GLP1RFOLH1
SCHEMBL29326632 0.98 GLP1R (0.47) GLP1RFOLH1
SCHEMBL31384214 0.93 GLP1R (0.56) GLP1RFOLH1
SCHEMBL31057892 0.90 GLP1R (0.44) GLP1RFOLH1
SCHEMBL24629587 0.89 GLP1R (0.54) GLP1RFOLH1
SCHEMBL29727716 0.89 GLP1R (0.54) GLP1RFOLH1
SCHEMBL31057679 0.87 SIRT5 (0.42) GLP1RFOLH1
SCHEMBL24630021 0.87 GLP1R (0.52) GLP1RFOLH1
SCHEMBL29727801 0.87 GLP1R (0.52) GLP1RFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238422-A1 Hypoimmunogenic Biotherapeutics ADAXION THERAPEUTICS, INC. 2024-07-18 — — US disclosed
US-20240238422-A1 Hypoimmunogenic Biotherapeutics ADAXION THERAPEUTICS, INC. 2024-07-18 — — US disclosed
EP-4274582-A1 HYPOIMMUNOGENIC BIOTHERAPEUTICS Osprey Biopharmaceuticals, Inc. (US) 2023-11-15 — — EP disclosed
WO-2022150726-A1 HYPOIMMUNOGENIC BIOTHERAPEUTICS OSPREY BIOPHARMACEUTICALS, INC. (US) 2022-07-14 — — WO disclosed
WO-2022150726-A1 HYPOIMMUNOGENIC BIOTHERAPEUTICS OSPREY BIOPHARMACEUTICALS, INC. (US) 2022-07-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238422-A1 Hypoimmunogenic Biotherapeutics FCGR3B, CD47, IL2 GLP1R 2531/4885FOLH1 614/4885ITGB3 1176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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