SCHEMBL24630340

SCHEMBL24630340

[N-]=[N+]=NCCOCCOCCC(=O)NCCCC[C@H](NC(=O)CCCNC(=O)CCOCCOCCN=[N+]=[N-])C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.49
▸ ALB P02768 8/20 0.46
▸ NOD1 Q9Y239 1/20 0.44
▸ FOLH1 Q04609 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29072106 1.00 GLP1R (0.49) GLP1RALBNOD1FOLH1
SCHEMBL24630070 0.96 GLP1R (0.51) GLP1RALBNOD1FOLH1
SCHEMBL29072104 0.96 GLP1R (0.51) GLP1RALBNOD1FOLH1
SCHEMBL26848385 0.88 FOLH1 (0.53) GLP1RFOLH1
SCHEMBL24629587 0.88 GLP1R (0.54) GLP1RFOLH1
SCHEMBL29727716 0.88 GLP1R (0.54) GLP1RFOLH1
SCHEMBL23337642 0.87 TGM2 (0.46) GLP1RALB
SCHEMBL13936440 0.86 GLP1R (0.49) GLP1RALBFOLH1
SCHEMBL13936446 0.86 GLP1R (0.49) GLP1RALBFOLH1
SCHEMBL13936443 0.86 GLP1R (0.49) GLP1RALBFOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240238422-A1 Hypoimmunogenic Biotherapeutics ADAXION THERAPEUTICS, INC. 2024-07-18 — — US disclosed
EP-4274582-A1 HYPOIMMUNOGENIC BIOTHERAPEUTICS Osprey Biopharmaceuticals, Inc. (US) 2023-11-15 — — EP disclosed
CN-116744944-A Low-immunogenicity biotherapeutic medicine 奥斯普瑞生物制药有限公司 2023-09-12 — — CN disclosed
WO-2022150726-A1 HYPOIMMUNOGENIC BIOTHERAPEUTICS OSPREY BIOPHARMACEUTICALS, INC. (US) 2022-07-14 — — WO disclosed
WO-2022150726-A1 HYPOIMMUNOGENIC BIOTHERAPEUTICS OSPREY BIOPHARMACEUTICALS, INC. (US) 2022-07-14 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240238422-A1 Hypoimmunogenic Biotherapeutics FCGR3B, CD47, IL2 GLP1R 2531/4885ALB 161/4885NOD1 1286/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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