Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.59 |
| ▸ | MC5R | P33032 | 1/20 | 0.57 |
| ▸ | MC3R | P41968 | 1/20 | 0.57 |
| ▸ | MC1R | Q01726 | 1/20 | 0.57 |
| ▸ | G6PD | P11413 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20619402 | 0.84 | ALDH1A1 (0.64) | HTR2AMEN1KMT2ALMNACYP1A2 | |
| SCHEMBL14907395 | 0.83 | HTR2A (0.71) | HTR2AMC5RMC3RMC1RG6PD | |
| SCHEMBL1726285 | 0.83 | HTR2A (0.71) | HTR2AMC5RMC3RMC1RG6PD | |
| SCHEMBL1726381 | 0.83 | HTR2A (0.71) | HTR2AMC5RMC3RMC1RG6PD | |
| SCHEMBL1724670 | 0.83 | HTR2A (0.71) | HTR2AMC5RMC3RMC1RG6PD | |
| SCHEMBL1725569 | 0.83 | HTR2A (0.71) | HTR2AMC5RMC3RMC1RG6PD | |
| SCHEMBL7022564 | 0.83 | HTR2A (0.71) | HTR2AMC5RMC3RMC1RG6PD | |
| SCHEMBL22411429 | 0.83 | HTR2A (0.71) | HTR2AMC5RMC3RMC1RG6PD | |
| SCHEMBL1727120 | 0.83 | HTR2A (0.71) | HTR2AMC5RMC3RMC1RG6PD | |
| SCHEMBL1725374 | 0.83 | HTR2A (0.71) | HTR2AMC5RMC3RMC1RG6PD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022150555-A2 | METHODS AND COMPOUNDS FOR TREATING FRIEDREICH'S ATAXIA | Design Therapeutics, Inc. (US) | 2022-07-14 | — | — | WO | disclosed |