⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22864283 | 0.80 | ADRB2 (0.35) | — | |
| SCHEMBL29593151 | 0.73 | F2RL1 (0.40) | — | |
| SCHEMBL28722165 | 0.73 | F2RL1 (0.40) | — | |
| SCHEMBL24631038 | 0.73 | F2RL1 (0.40) | — | |
| SCHEMBL28722132 | 0.69 | ADRB2 (0.40) | — | |
| SCHEMBL20531570 | 0.66 | DGAT1 (0.34) | — | |
| SCHEMBL9906852 | 0.66 | DGAT1 (0.34) | — | |
| SCHEMBL20746008 | 0.64 | MAPT (0.38) | — | |
| SCHEMBL30595139 | 0.64 | MAPT (0.38) | — | |
| SCHEMBL25021669 | 0.64 | NPC1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220315534-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | CURASEN THERAPEUTICS, INC. | 2022-10-06 | — | — | US | disclosed |
| EP-3993878-A1 | BETA ADRENERGIC AGONIST AND METHODS OF USING THE SAME | Curasen Therapeutics, Inc. (US) | 2022-05-11 | — | — | EP | disclosed |