Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | GCK | P35557 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24632522 | 0.86 | HTR2A (0.42) | NPC1RAB9AMEN1KMT2ATAS1R3 | |
| SCHEMBL25085619 | 0.83 | SMN1; SMN2 (0.45) | NPC1RAB9AGCKMEN1ALDH1A1 | |
| SCHEMBL21267605 | 0.83 | PDE2A (0.43) | GCKMEN1ALDH1A1KMT2AEPHX1 | |
| SCHEMBL24632926 | 0.81 | OPRL1 (0.40) | DRD4OPRL1 | |
| SCHEMBL16962148 | 0.79 | SLC6A2 (0.43) | DRD4OPRL1 | |
| SCHEMBL24632526 | 0.75 | HCRTR2 (0.43) | ALDH1A1KMT2A | |
| SCHEMBL18503369 | 0.73 | SLC6A2 (0.39) | TAS1R3TAS1R1TAS1R2DRD4OPRL1 | |
| SCHEMBL13499926 | 0.72 | PTGDR2 (0.42) | NPC1RAB9ADRD4OPRL1 | |
| SCHEMBL14864497 | 0.71 | PTGDR2 (0.44) | NPC1RAB9AOPRL1LMNA | |
| SCHEMBL10282411 | 0.71 | TAS1R3 (0.62) | NPC1RAB9AMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022236253-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | NUVATION BIO INC. (US) | 2022-11-10 | — | — | WO | disclosed |
| WO-2022236256-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | NUVATION BIO INC. (US) | 2022-11-10 | — | — | WO | disclosed |