SCHEMBL2463280

SCHEMBL2463280

C=C(C)COC(C)C(=O)OCCCCOC(=O)C(C)OCC(=C)C

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.39
ALDH1A1 P00352 2/20 0.33
CYP3A4 P08684 1/20 0.32
NAAA Q02083 1/20 0.31
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
HTT P42858 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2466487 0.92 TSHR (0.36) TSHRALDH1A1
SCHEMBL25087196 0.82 ALDH1A1 (0.39) TSHRALDH1A1
SCHEMBL25086852 0.82 ALDH1A1 (0.39) TSHRALDH1A1
SCHEMBL2464777 0.81 FAAH (0.33) TSHR
SCHEMBL2462875 0.79 TSHR (0.33) TSHR
SCHEMBL25087195 0.76 TSHR (0.33) TSHR
SCHEMBL24034198 0.76 TSHR (0.33) TSHR
SCHEMBL30343522 0.76 ALDH1A1 (0.50) TSHRALDH1A1NAAAHTTTDP1
SCHEMBL25087124 0.76 TSHR (0.33) TSHR
SCHEMBL1025317 0.75 TSHR (0.34) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1632281-B1 Process for absorbing hydrophobic substances in polymers having an hollow structure ROHM & HAAS (US) 2011-09-14 EP disclosed
EP-1510318-B1 Process for manufacturing polymers ROHM & HAAS (US) 2009-07-01 EP disclosed
US-7312259-B2 combining polymers with surfactants having hydrophilic-lipophilic balance values between 10 and 25 via spray drying, to lower or reduce the dusting levels, raise the minimum ignition energy and lower explosion strength during handling, conveying and storage ROHM AND HAAS COMPANY (US) 2007-12-25 US disclosed
EP-1092421-B1 Method for preparing ultraviolet radiation absorbing compositions ROHM & HAAS (US) 2007-03-21 EP disclosed
US-7192542-B2 Oil absorbing composition and process ROHM AND HAAS COMPANY (US) 2007-03-20 US disclosed
EP-1632281-A1 Process for absorbing hydrophobic substances in polymers having an hollow structure ROHM AND HAAS COMPANY (US) 2006-03-08 EP disclosed
US-20050203215-A1 Polymer carriers and process UGAZIO STEPHEN P J (FR) 2005-09-15 US disclosed
EP-1574534-A1 Polymer carriers and process ROHM AND HAAS COMPANY (US) 2005-09-14 EP disclosed
US-20050131143-A1 Oil absorbing composition and process ROHM AND HAAS FRANCE, S.A.S. (FR) 2005-06-16 US disclosed
EP-1514658-A1 Process for manufacturing polymers ROHM AND HAAS COMPANY (US) 2005-03-16 EP disclosed
EP-1510318-A1 Process for manufacturing polymers ROHM AND HAAS COMPANY (US) 2005-03-02 EP disclosed
US-20050043458-A1 Process for manufacturing polymers ROHM AND HAAS COMPANY 2005-02-24 US disclosed
US-20050043453-A1 Process for manufacturing polymers CHANG CHING-JEN (US) 2005-02-24 US disclosed
US-6384104-B1 PROVIDING STORAGE STABILITY TO ULTRAVIOLET RADIATION ABSORPTION COMPOSITIONS BY ADDING LATEX POLYMER PARTICLES TO INCREASE ABSORPTION, WHEREIN PARTICLES CONTAIN VOID, HAVE SPECIFIED PARTICLE SIZE AND COMPRISE CROSSLINKED SHELL PORTION ROHM AND HAAS COMPANY 2002-05-07 US disclosed
EP-1092421-A2 Method for preparing ultraviolet radiation absorbing compositions ROHM AND HAAS COMPANY (US) 2001-04-18 EP disclosed