SCHEMBL24633262

SCHEMBL24633262

CC(C)(c1ccccc1)c1ccc(OP(Oc2ccccc2)Oc2ccccc2)cc1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
ESR1 P03372 1/20 0.50
CYP3A4 P08684 1/20 0.50
ESR2 Q92731 1/20 0.50
KMT2A Q03164 6/20 0.46
MEN1 O00255 5/20 0.46
KDM4E B2RXH2 7/20 0.43
POLB P06746 2/20 0.43
HTT P42858 1/20 0.42
NR3C2 P08235 3/20 0.41
MAPK1 P28482 1/20 0.40
NPC1 O15118 1/20 0.40
RAB9A P51151 1/20 0.40
LMNA P02545 2/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2242361 0.98 ALDH1A1 (0.52) ALDH1A1SMN1; SMN2ESR1CYP3A4ESR2
SCHEMBL8038458 0.98 SMN1; SMN2 (0.47) ALDH1A1SMN1; SMN2ESR1CYP3A4ESR2
Bisphenol A SCHEMBL25286041 0.87 ESR1 (0.66) ALDH1A1SMN1; SMN2ESR1CYP3A4ESR2
SCHEMBL9441893 0.86 MAPT (0.49) ALDH1A1SMN1; SMN2KMT2AMEN1KDM4E
SCHEMBL9441933 0.86 MAPT (0.49) ALDH1A1SMN1; SMN2KMT2AMEN1KDM4E
SCHEMBL2242362 0.82 ALDH1A1 (0.53) ALDH1A1SMN1; SMN2ESR1CYP3A4ESR2
SCHEMBL24633257 0.82 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2ESR1CYP3A4ESR2
SCHEMBL9248118 0.81 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2ESR1CYP3A4ESR2
SCHEMBL13283512 0.79 HPGD (0.39) ALDH1A1SMN1; SMN2ESR1CYP3A4ESR2
SCHEMBL19149234 0.79 KDM4E (0.44) ALDH1A1SMN1; SMN2ESR1CYP3A4ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11674041-B2 Stabilizer composition for polymer-composition melt processing and related methods DOVER CHEMICAL CORPORATION 2023-06-13 US disclosed
US-11674041-B2 Stabilizer composition for polymer-composition melt processing and related methods DOVER CHEMICAL CORPORATION 2023-06-13 US disclosed
US-20220380600-A1 Stabilizer Composition For Polymer-Composition Melt Processing and Related Methods DOVER CHEMICAL CORPORATION 2022-12-01 US disclosed