Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | ESRRG | P62508 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24633262 | 0.98 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1ESR1CYP3A4ESR2 | |
| SCHEMBL2242361 | 0.96 | ALDH1A1 (0.52) | SMN1; SMN2ALDH1A1ESR1CYP3A4ESR2 | |
| Bisphenol A SCHEMBL25286041 | 0.89 | ESR1 (0.66) | SMN1; SMN2ALDH1A1ESR1CYP3A4ESR2 | |
| SCHEMBL9441893 | 0.88 | MAPT (0.49) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9441933 | 0.88 | MAPT (0.49) | SMN1; SMN2ALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL13283512 | 0.81 | HPGD (0.39) | SMN1; SMN2ALDH1A1ESR1CYP3A4ESR2 | |
| SCHEMBL24633257 | 0.81 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1ESR1CYP3A4ESR2 | |
| SCHEMBL2463038 | 0.80 | LTA4H (0.57) | SMN1; SMN2ALDH1A1ESR1CYP3A4ESR2 | |
| SCHEMBL2703544 | 0.80 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1ESR1CYP3A4ESR2 | |
| SCHEMBL2242362 | 0.80 | ALDH1A1 (0.53) | SMN1; SMN2ALDH1A1ESR1CYP3A4ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6133379-A | MELT MIXING THE POLYMERIC BLENDS CONTAINING VARIABLE RATIO OF VOLATILE COMPONENTS, FEEDING THE BLEND FROM A FIRST SUPPLY PORT OF MELT KNEADER, REMOVING VOLATILE UNDER REDUCED PRESSURE AND FEEDING A THIRD THERMOPLSTIC RESIN FROM SENCOND PORT | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 2000-10-17 | — | — | US | claimed |
| EP-3498469-B1 | LAMINATE CONTAINING POLYCARBONATE COMPOSITION LAYERS AND FIBER STRUCTURE LAYERS WITH IMPROVED FIRE RESISTANCE PROPERTIES | TRINSEO EUROPE GMBH (CH) | 2021-12-01 | — | — | EP | disclosed |
| EP-3498469-A1 | LAMINATE CONTAINING POLYCARBONATE COMPOSITION LAYERS AND FIBER STRUCTURE LAYERS WITH IMPROVED FIRE RESISTANCE PROPERTIES | Trinseo Europe GmbH (CH) | 2019-06-19 | — | — | EP | disclosed |
| US-6133379-A | MELT MIXING THE POLYMERIC BLENDS CONTAINING VARIABLE RATIO OF VOLATILE COMPONENTS, FEEDING THE BLEND FROM A FIRST SUPPLY PORT OF MELT KNEADER, REMOVING VOLATILE UNDER REDUCED PRESSURE AND FEEDING A THIRD THERMOPLSTIC RESIN FROM SENCOND PORT | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 2000-10-17 | — | — | US | disclosed |