Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 3/20 | 0.35 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20448940 | 0.76 | GAA (0.46) | PTPN1PTPN2 | |
| SCHEMBL8234959 | 0.67 | PTPN1 (0.60) | PTPN1PTPN2 | |
| SCHEMBL20533682 | 0.66 | LPL (0.39) | — | |
| SCHEMBL25948851 | 0.63 | PTPN1 (0.37) | PTPN1PTPN2 | |
| SCHEMBL15344940 | 0.61 | KDM4E (0.42) | PTPN1PTPN2 | |
| SCHEMBL13483977 | 0.60 | PTPN1 (0.35) | PTPN1PTPN2 | |
| SCHEMBL15333310 | 0.59 | PTPN1 (0.34) | PTPN1PTPN2 | |
| SCHEMBL8112774 | 0.59 | KDM4E (0.55) | — | |
| SCHEMBL21863289 | 0.57 | MAPT (0.40) | PTPN1PTPN2 | |
| SCHEMBL15341828 | 0.57 | SMN1; SMN2 (0.33) | PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022240830-A1 | C-LINKED INHIBITORS OF ENL/AF9 YEATS | BRIDGE MEDICINES (US) | 2022-11-17 | — | — | WO | disclosed |