Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.36 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.30 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8741924 | 0.89 | FPR2 (0.47) | FPR2CXCR2NAALAD2MMP8CTSS | |
| SCHEMBL9147437 | 0.89 | FPR2 (0.47) | FPR2CXCR2NAALAD2MMP8CTSS | |
| SCHEMBL24633935 | 0.82 | TSHR (0.40) | FPR2NAALAD2SMN1; SMN2 | |
| SCHEMBL8995757 | 0.79 | FPR2 (0.50) | FPR2CXCR2NAALAD2MMP8CTSS | |
| SCHEMBL8995750 | 0.79 | FPR2 (0.50) | FPR2CXCR2NAALAD2MMP8CTSS | |
| SCHEMBL8995753 | 0.79 | FPR2 (0.50) | FPR2CXCR2NAALAD2MMP8CTSS | |
| SCHEMBL10575333 | 0.77 | FPR2 (0.49) | FPR2CXCR2NAALAD2MMP8CTSS | |
| SCHEMBL10575336 | 0.77 | FPR2 (0.49) | FPR2CXCR2NAALAD2MMP8CTSS | |
| SCHEMBL24633806 | 0.76 | NAALAD2 (0.44) | NAALAD2GAA | |
| SCHEMBL24633811 | 0.74 | NAALAD2 (0.35) | NAALAD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234853-A1 | CYCLIC COMPOUND HAVING INHIBITORY EFFECT SELECTIVE FOR KRAS BUT NOT FOR HRAS AND NRAS | 中外製薬株式会社 | 2022-11-10 | — | — | WO | disclosed |