Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FPR2 | P25090 | 1/20 | 0.50 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8995757 | 1.00 | FPR2 (0.50) | FPR2NAALAD2CXCR2ALDH1A1CTSS | |
| SCHEMBL8995753 | 1.00 | FPR2 (0.50) | FPR2NAALAD2CXCR2ALDH1A1CTSS | |
| SCHEMBL10575333 | 0.82 | FPR2 (0.49) | FPR2NAALAD2CXCR2CTSSMMP8 | |
| SCHEMBL10575336 | 0.82 | FPR2 (0.49) | FPR2NAALAD2CXCR2CTSSMMP8 | |
| SCHEMBL18484564 | 0.82 | CNR2 (0.38) | FPR2ALDH1A1CTSSMMP8TDP1 | |
| SCHEMBL13544391 | 0.80 | NAALAD2 (0.47) | FPR2NAALAD2ALDH1A1MMP2MMP13 | |
| SCHEMBL5607969 | 0.80 | NAALAD2 (0.47) | FPR2NAALAD2ALDH1A1MMP2MMP13 | |
| SCHEMBL608376 | 0.80 | NAALAD2 (0.37) | FPR2NAALAD2ALDH1A1CTSSSMN1; SMN2 | |
| SCHEMBL24633802 | 0.79 | FPR2 (0.47) | FPR2NAALAD2CXCR2CTSSMMP8 | |
| SCHEMBL8741924 | 0.79 | FPR2 (0.47) | FPR2NAALAD2CXCR2ALDH1A1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5492830-A | CONTACTING RACEMIC ESTER IN AQUEOUS MEDIUM WITH SERINE CARBOXYPEPTIDASE TO HYDROLYZE S-ENANTIOMER PREFERENTIALLY | GENZYME CORPORATION (US) | 1996-02-20 | — | — | US | disclosed |