Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 7/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GLS | O94925 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8294191 | 0.69 | L3MBTL1 (0.39) | DPP4L3MBTL1 | |
| SCHEMBL8294196 | 0.69 | L3MBTL1 (0.42) | ALDH1A1DPP4L3MBTL1 | |
| SCHEMBL14421459 | 0.68 | DPP4 (0.43) | DPP4GLS | |
| SCHEMBL24900230 | 0.68 | DPP4 (0.43) | DPP4GLS | |
| SCHEMBL14097634 | 0.67 | DPP4 (0.46) | DPP4GLS | |
| Hydrochloric Acid SCHEMBL3213539 | 0.67 | DPP4 (0.42) | DPP4 | |
| SCHEMBL1174765 | 0.67 | DPP4 (0.46) | DPP4GLS | |
| SCHEMBL1174761 | 0.67 | DPP4 (0.46) | DPP4GLS | |
| Hydrochloric Acid SCHEMBL3213524 | 0.67 | DPP4 (0.42) | DPP4 | |
| SCHEMBL6687939 | 0.66 | ALDH1A1 (0.41) | ALDH1A1DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022234853-A1 | CYCLIC COMPOUND HAVING INHIBITORY EFFECT SELECTIVE FOR KRAS BUT NOT FOR HRAS AND NRAS | 中外製薬株式会社 | 2022-11-10 | — | — | WO | disclosed |