Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23611455 | 0.97 | HTR3A (0.34) | HTR3AHRH4 | |
| SCHEMBL6696059 | 0.94 | HTR3A (0.35) | HTR3AHRH4 | |
| SCHEMBL4983000 | 0.94 | — | — | |
| SCHEMBL3155486 | 0.94 | — | — | |
| SCHEMBL6585017 | 0.91 | HTR3A (0.39) | HTR3AHRH4 | |
| SCHEMBL1524741 | 0.91 | HTR3A (0.39) | HTR3AHRH4 | |
| SCHEMBL1524762 | 0.91 | HTR3A (0.39) | HTR3AHRH4 | |
| SCHEMBL2334878 | 0.91 | HTR3A (0.39) | HTR3AHRH4 | |
| SCHEMBL15552104 | 0.91 | HTR3A (0.39) | HTR3AHRH4 | |
| SCHEMBL2708905 | 0.90 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011110367-A2 | METHOD OF SCREENING FOR HTRA PROTEASE INHIBITORS USEFUL FOR PROPHYLAXIS AND THERAPY OF A BACTERIAL INFECTION | PAUL-EHRLICH-INSTITUT (DE) | 2011-09-15 | — | — | WO | disclosed |
| EP-2365091-A1 | Method of screening for HtrA protease inhibitors useful for prophylaxis and therapy of a bacterial infection | Paul-Ehrlich-Institut (DE) | 2011-09-14 | — | — | EP | disclosed |