Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24633970 | 0.86 | CA1 (0.36) | CA1CA2 | |
| SCHEMBL18099486 | 0.84 | DGAT1 (0.31) | — | |
| SCHEMBL17420920 | 0.79 | GABRA1 (0.33) | CA1CA2 | |
| SCHEMBL24633968 | 0.78 | POLB (0.35) | CA1CA2 | |
| SCHEMBL22805144 | 0.76 | NMT1 (0.34) | — | |
| SCHEMBL1630637 | 0.74 | ERN1 (0.36) | — | |
| SCHEMBL26084697 | 0.74 | CA1 (0.31) | CA1CA2 | |
| SCHEMBL5305665 | 0.72 | HDAC1 (0.35) | — | |
| SCHEMBL12986534 | 0.72 | GABRA1 (0.41) | — | |
| SCHEMBL13550059 | 0.72 | NQO2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4309741-A1 | CYCLIC COMPOUND HAVING INHIBITORY EFFECT SELECTIVE FOR KRAS BUT NOT FOR HRAS AND NRAS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-01-24 | — | — | EP | disclosed |
| WO-2023214576-A1 | CYCLIC COMPOUND HAVING SELECTIVE KRAS INHIBITORY EFFECT ON HRAS AND NRAS | 中外製薬株式会社 | 2023-11-09 | — | — | WO | disclosed |
| WO-2022234853-A1 | CYCLIC COMPOUND HAVING INHIBITORY EFFECT SELECTIVE FOR KRAS BUT NOT FOR HRAS AND NRAS | 中外製薬株式会社 | 2022-11-10 | — | — | WO | disclosed |