Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22805144 | 0.85 | NMT1 (0.34) | NMT1 | |
| SCHEMBL24633968 | 0.84 | POLB (0.35) | NMT1 | |
| SCHEMBL10506747 | 0.74 | NMT1 (0.37) | NMT1 | |
| SCHEMBL31292460 | 0.74 | NMT1 (0.33) | NMT1 | |
| SCHEMBL18099486 | 0.72 | DGAT1 (0.31) | — | |
| SCHEMBL6600235 | 0.71 | NMT1 (0.42) | NMT1 | |
| SCHEMBL981107 | 0.70 | NMT1 (0.34) | NMT1 | |
| SCHEMBL2413799 | 0.70 | MAPK1 (0.35) | — | |
| SCHEMBL24633970 | 0.70 | CA1 (0.36) | — | |
| SCHEMBL10872330 | 0.69 | ALDH1A1 (0.53) | NMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4309741-A1 | CYCLIC COMPOUND HAVING INHIBITORY EFFECT SELECTIVE FOR KRAS BUT NOT FOR HRAS AND NRAS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2024-01-24 | — | — | EP | disclosed |
| WO-2022234853-A1 | CYCLIC COMPOUND HAVING INHIBITORY EFFECT SELECTIVE FOR KRAS BUT NOT FOR HRAS AND NRAS | 中外製薬株式会社 | 2022-11-10 | — | — | WO | disclosed |